骨肿瘤样病变的^(18)F-FDG PET/CT表现  

Manifestations of ^(18)F-FDG PET/CT scanning in tumor-like lesions of bone

作　　者：丁重阳[1] 李天女[1] 吉爱兵[2] 

机构地区：[1]南京医科大学第一附属医院核医学科,江苏南京210029 [2]江苏大学附属宜兴医院核医学科,江苏无锡214200

出　　处：《中国医学影像技术》2014年第10期1561-1564,共4页Chinese Journal of Medical Imaging Technology

基　　金：南京市科技计划项目(201303038)

摘　　要：目的探讨骨肿瘤样病变的^(18)F-FDG PET/CT显像特征。方法回顾性分析经病理证实的10例骨肿瘤样病变患者的^(18)F-FDG PET/CT显像资料,其中骨嗜酸性肉芽肿4例,骨纤维异常增殖症及动脉瘤样骨囊肿各3例。结果10例骨肿瘤样病变中,9例为单发病灶,1例为多发病灶。发生于肋骨5例,脊柱3例,肱骨及顶骨各1例。骨嗜酸性肉芽肿^(18)F-FDG PET/CT表现为不同程度的骨质破坏,^(18)F-FDG摄取均匀性增高,SUV_(max)为6.1~15.4;骨纤维异常增殖症^(18)F-FDG PET/CT表现为溶骨性骨质破坏,但邻近脂肪间隙存在,^(18)F-FDG摄取不同程度增高,SUV…为3.8~6.3。动脉瘤样骨囊肿^(18)F-FDG PET/CT表现为膨胀性囊状或皂泡样骨质破坏,边缘可见硬化环,^(18)F-FDG摄取不均匀性增高,SUV_(max)为2.8~6.9。三者间SUV_(max)差异无统计学意义(x^2=4.564,P=0.102)。结论骨肿瘤样病变^(18)F-FDGPET/CT表现具有一定特征,有助于临床诊断。Objective To study the manifestations of 18F-FDG PET/CT in tumor-like lesions of bone. Methods 18F-FDG PET/CT manifestations of ten patients with pathology proved tumor-like lesions of bone were retrospectively analyzed, including eosinophilic granuloma of bone 4 cases, fibrous dysplasia of bone 3cases and aneurysmal bone cyst 3cases. Results Among 10 cases, there were 9 cases with single and 1 case with multiple lesions. Five cases were located in rib, 3 cases in vertebral column, 1 case in cranial bone and 1 case in humerus. 18F-FDG PET/CT of eosinophilic granuloma of bone showed inordinately bone destruction with homogeneity intensity uptake of 18 F-FDG （SUVmax ranging of 6.1 to 15.4）. Fibrous dysplasia of bone showed osteolytic destruction with inordinately uptake of 18 F-FDG （SUVmax ranging of 3.8 to 6.3）, but the surrounding fat gap was existed. Aneurysmal bone cyst showed cystic or soap-bubble like bone destruction with hardening ring edges and heterogeneous uptake of 18F-FDG （SUVmax ranging of 2.8 to 6.9）. There was no differences of SUVmax among eosinophilic granuloma of bone, fibrous dysplasia of bone and aneurysmal bone cyst （X2= 4.564, P=0.102）. Conclusion The 18F-FDG PET/CT manifestation of tumor-like lesions of bone has certain characteristics, which is helpful for clinical diagnosis.

关 键 词：体层摄影术 发射型计算机 18F氟脱氧葡萄糖 肿瘤样病变 

分 类 号：R738[医药卫生—肿瘤] R814.42[医药卫生—临床医学]