后房型有晶状体眼人工晶状体植入术矫正超高度近视的视觉质量研究  

Visual quality after phakic posterior chamber intraocular lens implantation for hyperhigh myopia

作　　者：王佼佼[1] 张立军[1] 牟亚男[1] 韩茜[1] 

机构地区：[1]大连市第三人民医院暨眼科医院视光学中心,辽宁省大连市116011

出　　处：《眼科新进展》2014年第10期946-949,共4页Recent Advances in Ophthalmology

基　　金：辽宁省大连市卫生局资助项目(编号:2011-246)~~

摘　　要：目的探讨后房型有晶状体眼人工矫正晶状体(intraocular corrective lens,ICL)植入术治疗超高度近视后患者的视觉质量。方法收集2010年2月至2012年12月就诊于我院的-10.0 D以上的接受后房型有晶状体眼ICL植入术治疗高度近视患者38例(76眼)为观察组,选取同期就诊于我院的-10.0 D以上的接受角膜屈光手术的患者31例(62眼)作为对照组。术前2组患者最佳矫正视力、对比敏感度、屈光状态等指标比较,差异均无统计学意义(均为P>0.05)。比较2组术前及术后10 d、1个月、3个月、6个月及12个月裸眼远近视力、最佳矫正视力、屈光度、波阵面相差及对比敏感度等。结果术后观察组患者各时间点随访的裸眼视力均超过术前最佳矫正视力,术后1个月及3个月2组裸眼视力比较均无统计学差异(均为P>0.05),术后12个月观察组裸眼视力为1.03±0.18、对照组裸眼视力为0.96±0.24,2组比较差异有统计学意义(t=2.040,P=0.025);观察组最佳矫正视力为1.05±0.17、对照组最佳矫正视力为1.06±0.17,2组差异无统计学意义(t=-0.341,P=0.970)。观察组术后高阶像差为(0.515±0.122)μm,与术前(0.400±0.060)μm相比差异无统计学意义(t=-7.825,P=0.128),对照组术后高阶像差为(0.818±0.151)μm,与术前(0.399±0.049)μm相比差异有统计学意义(t=22.580,P=0.037),2组术后高阶像差相比差异有统计学意义(t=13.049,P=0.005)。观察组术后1个月对比敏感度恢复到术前水平,对照组对比敏感度始终低于术前,各时间点观察组对比敏感度均优于对照组,差异均有显著统计学意义。结论 ICL植入术对于超高度近视的矫正较准分子激光原位角膜磨镶术更安全、稳定、有效。Objective To explore the visual quality after phakic posterior chamber intraocular corrective lens（ICL） implantation for hyper-high myopia. Methods A total of 76 high myopia eyes with diopter more than- 10. 00 D of 38 patients in our hospital from February 2010 to December 2012 accepted of posterior chamber phakic ICL implantation as observation group,and62 high myopia eyes with similar diopter as above group of 38 patients accepted LASIK were selected as control group. The patients were followed up for 12 months,the uncorrected distant and near visual acuity,best corrected visual acuity（ BCVA）,diopter,wavefront aberration and contrast sensitivity before surgery and 10 days,1 month,3 months,6 months,12 months after surgery were examined and compared. Results The postoperative uncorrected visual acuity at every time of observation group was better than the preoperative BCVA,there was no statistical difference in uncorrected visual acuity at postoperative 1 month and 3 months between two groups（all P 〉0.05）. At postoperative 12 months,the uncorrected visual acuity of observation group was 1. 03 ±0. 18,the control group was 0. 96 ± 0. 24,the difference was statistically significant（t = 2. 040,P= 0. 025）. BCVA of observation group was 1. 05 ± 0. 17,and the control group was 1. 06 ± 0. 17,there was no significant difference（t =- 0. 341,P = 0. 970）. The postoperative high-order aberration of observation group was（0. 515 ± 0. 122） μm,compared with pre-operation（0. 400 ± 0.060）μm,there was no statistical difference（t =- 7. 825,P = 0. 128）;The postoperative high-order aberration of observation group was（0. 818 ± 0. 151） μm,compared with pre-operation（0.399 ± 0. 049）μm,there was statistical difference（t = 22. 580,P = 0. 037）. There was statistical difference in postoperative high-order aberration between two groups（t = 13. 049,P = 0. 005）. About 1 month after operation the contrast sensitivity of patients in the observation group returned to the level of pre-ope

关 键 词：人工晶状体 超高度近视 视觉质量 

分 类 号：R776.1[医药卫生—眼科]