脑小血管病患者认知损害的机制和筛查  

Mechanisms and screening for cognitive impairment in patients with cerebral small vessel disease

作　　者：尚成镇 杨昆胜[1] 

机构地区：[1]昆明医科大学第一附属医院神经内科,650032

出　　处：《国际脑血管病杂志》2014年第9期677-681,共5页International Journal of Cerebrovascular Diseases

摘　　要：脑小血管病是指主要累及颅内小动脉和微动脉的一组疾病。脑小血管病在MRI上的主要特征性改变为弥漫性白质高信号、腔隙性梗死、微出血和血管周围间隙扩大，这些改变可能与认知损害存在相关性。目前，已有多种量表可用于脑小血管病所致认知损害的评价。Cerebral small vessel disease is a group of diseases mainly affecting intracranial small artery and arteriole. The main characteristic changes of cerebral small vessel disease on MRI are diffuse white matter hyperintensities, lacunar infarcts, cerebral microbleeds, and enlarged perivascular spaces. These changes may be correlated with cognitive impairment. At present, many scales are available and can be used to evaluate cerebral small vessel disease caused cognitive impairment.

关 键 词：脑小血管疾病 认知障碍 脑血管障碍 神经心理学测验 

分 类 号：R749.16[医药卫生—神经病学与精神病学]