辣椒素抗癌作用及其机制研究进展  

Advances on Capsaicin Anti-cancer Activity and its Mechanism of Action

作　　者：谢乐[1] 周慎[2] 伍大华[2] 向光红[3] 唐涛[4] 唐劲天[5] 

机构地区：[1]湖南中医药大学,湖南长沙410208 [2]湖南省中医药研究院附属医院脑病科,湖南长沙410006 [3]湖南省脑科医院神经内科,湖南长沙410007 [4]北京大北农科技集团股份有限公司饲用微生物工程国家重点实验室,北京100192 [5]清华大学工程物理系医学物理与工程研究所,北京100084

出　　处：《湖南中医药大学学报》2014年第9期58-61,共4页Journal of Hunan University of Chinese Medicine

基　　金：国家国际科技合作计划资助项目(2011DFA30620)

摘　　要：辣椒素是辣椒产生火辣感的主要成分,近年国内外研究表明辣椒素具有良好的抗癌功效。辣椒素具有抑制癌细胞增殖,促进癌细胞凋亡、坏死,抑制癌细胞转移,增加抗癌药物敏感性,增强机体对癌细胞的免疫杀伤力和改善癌细胞导致的机体代谢紊乱等作用。辣椒素能通过多种途径发挥抗癌作用,表明辣椒素有望成为新型的抗癌药物。Capsaicin is the main active pungent ingredient in hot chilli peppers. In recent years, domestic and foreign researches show that capsaicin has good anti-cancer effects. Capsaicin can restrain the proliferation of cancer cell, promote its apoptosis and necrosis, inhibit cancer metastasis, increase the sensitivity of anti-cancer drugs and the body＇s immunity of cancer cells, ameliorate metabolic disturbances caused by cancer. So capsaicin has a great potential to become a new anti-cancer agent, as it can play anti-cancer effects by multi-approaches

关 键 词：辣椒素 抗癌作用 抗癌机制 

分 类 号：R285[医药卫生—中药学] R73[医药卫生—中医学]