大肠癌T分期及N分期相关因素分析  

Analysis of factors related to depth invasion and lymph node metastasis in colorectal cancer

作　　者：李世正[1] 张俊华[1] 董哲[1] 张银旭[1] 黄野 

机构地区：[1]辽宁医学院附属第一医院普通外科,辽宁锦州121001

出　　处：《中国现代医学杂志》2014年第26期64-66,共3页China Journal of Modern Medicine

基　　金：辽宁省自然科学基金(No:2011225015)

摘　　要：目的探讨大肠癌T分期及N分期的相关因素,为临床诊断与治疗提供参考。方法对该院2012年6月至2012年12月施行根治性手术的109例大肠癌病理资料进行分类整理,用χ2检验分析肿瘤环肠壁生长情况与T分期及肿瘤浸润深度与N分期的关系。结果大肠癌环肠壁侵犯越广泛,肿瘤肠壁浸润深度越深,环肠壁大于1/2周者肿瘤浸润肠壁全层比例达82.5%。肿瘤浸润深度未超过浅肌层者无淋巴结转移;超过浅肌层者,淋巴结转移率达61.9%。结论大肠癌肠壁浸润深度与肿瘤环肠壁生长情况呈正相关;肿瘤浸润深度超过浅肌层可作为淋巴结转移的高危因素,为临床手术术式选择提供依据。[Objective] Investigated the factors related to depth invasion and lymph node metastasis of colorectal carcinoma, in order to provide reference for clinical diagnosis and treatment. [Methods] A retro- spective analysis was performed in the 109 patients with colorectal carcinoma who had underwent radical re- section from June 2012 to December 2012 in this hospital. The relations between depth invasion and lymph node metastasis and clinieopathologic variables were evaluated by Chi-square test. [Results] The more col- orectal cancer infiltrate ring wall extensive, the more depth invasions. When tumor infihrate wall more than 1/ 2 circle, the ratio of full-thickness wall invasion reached 82.5%. There was on lymph node metastasis when depth invasions less than superficial muscle. The ratio of lymph node metastasis reached 61.9% when depth invasions expanded beyond superficial muscle. [Conclusion] There was a positively correlation between depth invasions and the situation of cancer ring grow. The depth invasions expanded beyond superficial muscle could be as risk factors of lymph node metastasis.

关 键 词：结直肠肿瘤 T分期 N分期 

分 类 号：R735.34[医药卫生—肿瘤]