肝硬化患者体表心电图QTc与Child-Pugh分级的关系  

Relationship between QTc of electrocardiogram and Child-Pugh grade of liver cirrhosis patients

作　　者：罗忠志[1] 康虹[1] 刘林勇[2] 

机构地区：[1]福建医科大学附属漳州市医院心电图室,363000 [2]福建医科大学附属漳州市医院保健科,363000

出　　处：《中国实用医药》2014年第27期27-28,共2页China Practical Medicine

摘　　要：目的探讨肝硬化患者体表心电图校正QT间期与Child-Pugh分级之间的关系。方法对161例肝硬化患者(肝硬化组)和同期100例健康体检者(健康对照组)进行QTc对比分析,并研究肝硬化患者QTc与Child-Pugh分级的关系。结果肝硬化患者心电图QTc较健康对照者明显延长,分别为(0.434±0.290)s和(0.382±0.180)s,(P<0.01)。且QTc和Child-Pugh分级相关,分级越高,QTc越长。A级:(0.409±0.224)s;B级:(0.438±0.259)s;C级:(0.455±0.174)s。不同Child-Pugh分级组内QTc两两比较,差异具有统计学意义(P<0.01)。结论肝硬化患者心电图QTc与病情严重程度呈正相关。Objective To investigate the relationship between rate-corrected QT interval（QTc） of electrocardiogram and Child-Pugh grade of liver cirrhosis patients. Methods A total of 161 cases of liver cirrhosis（liver cirrhosis group） and 100 cases of healthy people（health control group） were analyzed of QTc. The relationship between QTc and Child-Pugh grade was studied. Results The QTc of electrocardiogram of liver cirrhosis group was more prolonged than the health control group [（0.434±0.290） s,（0.382±0.180） s, P〈0.01）]. QTc was positively correlated with Child-Pugh grade. Grade A was（0.409±0.224） s; grade B was（0.438±0.259） s; grade C was（0.455±0.174） s. The differences of QTc in different Child-Pugh grades were statistically significant（P〈0.01）. Conclusion The QTc of liver cirrhosis patients is positively correlated with the severity of liver cirrhosis.

关 键 词：校正QT间期 肝硬化 CHILD-PUGH分级 

分 类 号：R575.2[医药卫生—消化系统]