Rapid analysis and identification for the alkaloids from Ranunculus japonicus by UPLC /Q-TOF-MS  

基于UPLC/Q-TOF-MS技术的毛茛生物碱类成分快速分析鉴定(英文)

作　　者：钟艳梅[1] 冯毅凡[1] 谭毓治[2] 

机构地区：[1]广东药学院中心实验室,广东广州510006 [2]广东药学院药理学教研室,广东广州510006

出　　处：《Journal of Measurement Science and Instrumentation》2014年第3期87-93,共7页测试科学与仪器（英文版）

摘　　要：To establish a rapid and effective method for analysis and identification of the alkaloids from Ranunculus japoni- cus Thunb by ultra-performance liquid chromatogaraphy with quadruple-time-of-flight mass spectrometry （UPLC/Q-TOF- MS） and discuss their fragmentation regularity, the UPLC/Q-TOF-MS was used to identify the alkaloids from Ranunculus japonicus Thunb by their MS data, tandem characteristic fragment ions and standards. In the end, 12 alkaloids were identi- fied from Ranunculus japonicus for the first time, and their fragmentation regularity was discussed. Thus, a rapid and effec- tive analysis and identification method for the alkaloids from Ranunculus japonicus by UPLC/Q-TOF-MS is established.

关 键 词：ALKALOIDS ultra-performance liquid chromatogaraphy with quadruple-time-of-flight mass spectrometry （UPLC/Q-TOF-MS） Ranunculus japonicas 

分 类 号：TQ464.4[化学工程—制药化工] O657.63[理学—分析化学]