老年脑梗死与颈动脉粥样硬化斑块的相关性及预后分析  

Analysis of correlation and prognosis between the elderly patients with cerebral infarction and the carotid atherosclerosis plaque

作　　者：冯靖雄[1] 邓强[1] 黄纯友[1] 张成贵[1] 

机构地区：[1]四川达州市中心医院神经内科,达州635000

出　　处：《中国实用神经疾病杂志》2014年第20期1-3,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的分析老年脑梗死与颈动脉粥样硬化斑块的相关性及预后的关系。方法选取100例老年脑梗死患者作为观察组和100例同期非脑梗死患者作为对照组,观察和比较2组颈动脉粥样硬化斑块情况、治疗前和治疗3个月、6个月后神经功能缺损评分(NIHSS评分)和日常生活活动能力评分(Barthel指数评分)。结果 2组颈动脉粥样硬化斑块检出率分别为86%和17%,观察组显著高于对照组(P<0.05),观察组软斑和混合斑的比例显著高于对照组(P<0.05),无斑块比例显著低于对照组(P<0.05);重型患者中有软斑和混合斑的比例显著高于中型患者(P<0.05),中型患者显著高于轻型患者(P<0.05);轻型患者中无斑块和有硬斑患者比例显著高于中型和重型患者(P<0.05);有软斑和混合斑患者治疗前和治疗后3个月、6个月的NIHSS评分显著高于有硬斑患者(P<0.05),有硬斑患者治疗前和治疗后3个月、6个月的NIHSS评分显著高于无斑块患者(P<0.05),有硬斑和无斑块患者在治疗3个月、6个月的Barthel指数评分显著高于有软斑和混合斑的患者(P<0.05)。结论颈动脉粥样硬化斑块的形成是与老年脑梗死发病具有相关性的危险因素,颈动脉粥样硬化斑块的类型与患者的病情具有相关性,有软斑和混合斑患者的神经功能损害和生活能力缺失症状更加严重、预后情况更差,有硬班和无斑块患者的神经功能损害症状较轻,预后情况较好。Objective To investigate the correlation and prognosis between the elderly patients with cerebral infarction and the carotid atherosclerosis plaque. Methods 100 cases of elderly patients with cerebral infarction were selected as the observa-tion group and 100 cases of elderly patients without cerebral infarction were selected as the control group. The carotid athero-sclerosis plaque ,neural function defect score （NIHSS score） and activities of daily living score （Barthel index score） were ob-served and compared before treatment and after treatment at the 3rd ,6th month. Results The detection rate of carotid athero-sclerosis plaque was 86% in observation group ang 17% in control group.There was mainly soft plaque or mixed plaque in the observation group ,which was higher than that in the control group. Heavy patients were given priority to soft and mixed plaque ,and light patients were given priority to with no plaque and hard spot. The NIHSS scores of patients with soft and mixed plaque were higher than these of patients with hard spot and the NIHSS and Barthel index scores of patients with hard spot were higher than these of patients with no plaque. Conclusion The carotid artery atherosclerotic plaque is a risk factor of elderly cerebral infarction. The nerve function impairment and life ability deficits of patients with soft or mixed plaque have more serious symptoms and prognosis than patients with no plaque and hard spot.

关 键 词：脑梗死 颈动脉 动脉粥样硬化 

分 类 号：R743.33[医药卫生—神经病学与精神病学]