胃转流术对2型糖尿病患者近期肠道菌群的影响  

The effect of Gastric Bypass on recent intestinal flora in type 2 diabetes patients

作　　者：苏德望[1] 杨春佳[2] 王跃生[1] 马淑霞[2] 王春敏[2] 

机构地区：[1]佳木斯大学附属第一医院普外一科,黑龙江佳木斯154002 [2]佳木斯大学基础医学院微生物教研室,黑龙江佳木斯154007

出　　处：《中国微生态学杂志》2014年第10期1146-1147,共2页Chinese Journal of Microecology

基　　金：黑龙江省自然基金(D201127)

摘　　要：目的研究2型糖尿病患者行胃转流术前后肠道菌群是否发生变化。方法收集30例2型糖尿病患者术前和术后粪便,测肠道菌群,以25例健康志愿者的粪便为对照组。结果 2型糖尿病患者的肠杆菌较健康人增多,双歧杆菌较正常人减少,胃转流术后双歧杆菌增加,肠杆菌减少。结论 2型糖尿病患者出现肠道菌群失调,胃转流术后控制了血糖,双歧杆菌数量增加。Objective To research changes of intestinal flora in patients with type 2 diabetes（ T2DM） before and after Gastric Bypass（ GBP）. Methods The feces samples of 30 patients with T2 DM before and after GBP were collected,then intestinal flora were measured; Samples of 25 healthy volunteers were used as the controls. Results Compared with healthy volunteers,E. coli in patients with type 2 diabetes increased while Bifidobacterium decreased. After accepted GBP,Bifidobacterium in T2 DM patients increased and E. coli decreased. Conclusion Patients with T2 DM occurred enteric dysbacteriosis. Gastric Bypass can control blood glucose and result in Bifidobacterium increase.

关 键 词：2型糖尿病 胃转流术 肠道菌群 

分 类 号：R378[医药卫生—病原生物学]