异位妊娠术后绒癌脑转移1例并文献复习  

Postoperative ectopic pregnancy with choriocarcinoma of brain metastases(a report of 1 case and review of literature)

作　　者：刘东媛 汪向红[1] 刘妮英[1] 范妮娜[1] 王丹[1] 张红波[2] 陈小奇[2] 穆林森[3] 张锦[4] 曾小君[4] 孙彦辉[4] 

机构地区：[1]湖北省新华医院妇产科,430015 [2]湖北省新华医院神经外科 [3]广州市脑科医院神经外科 [4]首都医科大学北京天坛医院神经外科

出　　处：《临床神经外科杂志》2014年第5期375-378,共4页Journal of Clinical Neurosurgery

摘　　要：目的报告1例异位妊娠术后绒癌脑转移瘤的病例并回顾文献。方法通过妇科及神经系统检查，病理及影像学结果确诊绒癌。急诊行腹腔镜下异位妊娠手术，切除孕囊及病变侧输卵管，术后病理示正常胚胎。术后随访6～12个月1例发生脑转移，予以开颅手术，病理报告绒癌。术后腰穿甲氨蝶呤化疗、脱水、激素等对症治疗。结果患者术后症状改善，随访6个月未见病变复发。结论异位妊娠术后发生绒癌脑转移瘤可见于育龄妇女，临床表现不典型，误诊率高。术后化疗为主的综合治疗可改善患者症状。Objective To report one case of postoperalive ectopic pregnancy with choriocarcinoma of brain metastases anti rexiew the literature. Methods Combined with gynecological,neurological, pathology and imaging examination the resuhs clearly confirmed choriocarcinoma. By undergone emergency ectopic pregnancy laparoscopic surgery to remove the lesion Oviduct anti Gestational sac,the postoperative pathology showed normal embryos. The follow up from 6 to 12 months showed a case was diagnosed brain metastases by craniolomy and pathological reports showed as choriocarcinoma. Lumbar puncture methotrexate chemothexapy, dehydration, hormones and other symptomatic treatment were underwent. Results The patients＇symptoms improved and no recurrent lesions were followed up for 6 months. Conclusions The postoperative ectopic pregnancy with choriocarcinoma of brain metastases occurrs in chidbecaring women age with atypical clinical manifestations anti high misdiagnosis. Chemotherapy combined therapy may improve symptoms in postoperative.

关 键 词：异位妊娠 绒癌 脑转移瘤 

分 类 号：R737.33[医药卫生—肿瘤]