血清肝纤四项检测在诊断原发性肝癌的应用  

Application of four items detection of liver fibrosis in serum to the diagnosis of primary hepatic carcinoma

作　　者：苑同业[1] 刘国凤 张立营[3] 

机构地区：[1]中国人民解放军401医院检验科,266071 [2]青岛市妇女儿童医院检验科,266034 [3]济南军区青岛第二疗养院检验科,266071

出　　处：《中国疗养医学》2014年第11期1023-1024,共2页Chinese Journal of Convalescent Medicine

摘　　要：目的探讨血清肝纤四项检测在诊断肝癌中的应用。方法采用化学发光法检测46例原发性肝癌、51例转移性肝癌、46例肝外恶性肿瘤患者血清PCⅢ、Ⅳ-C、LN和HA的含量。结果原发性肝癌组PCⅢ、Ⅳ-C、LN和HA水平明显高于转移性肝癌组和肝外恶性肿瘤组(P<0.05)。结论肝纤四项指标与原发性肝癌关系密切,血清肝纤四项检测对原发性肝癌肝纤维化程度的判断、鉴别转移性肝癌有一定的价值。Objective To study the application of four item s detection of liver fibrosis in serum to the diagnosis of prim ary hepatic carci-nom a.Methods The levels of the serum PCⅢ,Ⅳ-C ,LN and HA were m easured by the m ethod of chem ilum inescence in 46 patients with prim ary hepatic carcinom a,51 patients with metastatic hepatic carcinom a,and 46 patients with extrahepatic m alignant tum or.Results The levels of the serum PCⅢ,Ⅳ-C ,LN and HA in the prim ary hepatic carcinom a group were higher than those in the metastatic hepatic carci-nom a group and the extrahepatic m alignant tum or group （P〈0 .05 ）.Conclusion The four fibrosis m arkers in serum were closely related to prim ary hepatic carcinom a,the measurem ent of which has certain value in the decision of hepatic fibrosis level in prim ary hepatic carcinoma and identification of metastatic hepatic carcinoma.

关 键 词：Ⅲ型前胶原 Ⅳ型胶原 层粘连蛋白 透明质酸 

分 类 号：R735.7[医药卫生—肿瘤]