前循环进展性卒中患者早期^(99m)Tc-ECD SPECT脑血流显像的影像特征和应用价值  

Imaging features and clinical value of brain ^(99)mTc-ECD single-photon emission CT study in the acute stage in patients with progressing stroke

作　　者：夏光明[1] 黄虎翔[1] 王洲羿[1] 金朝霞[1] 肖展翅 王洪敏[1] 王昌权[1] 李钢[1] 

机构地区：[1]长江大学附属黄冈市中心医院神经内科,湖北黄冈438000

出　　处：《中风与神经疾病杂志》2014年第10期926-928,共3页Journal of Apoplexy and Nervous Diseases

基　　金：湖北省卫生厅科研基金项目(No.JX4B72)

摘　　要：目的探讨99 mTc SPECT局部脑血流显像在进展性卒中早期诊断中的价值。方法通过61例经CT或MR确诊的急性脑梗死患者24 h内进行SPECT脑血流显像检查,根据病情进展分为进展性卒中组和非进展性卒中组。结果进展性卒中组(18例)SPECT脑血流显像均表现有不同程度的交叉性小脑神经联系不能,而非进展性卒中(43例)仅有2例出现。按照AI判定CCD标准,均以AI>0.1为参考值,进展性脑卒中CCD为1.44±0.45(t=12.18 P<0.0005),有显著统计学意义;非进展性脑卒中CCD为0.05±0.06(t=0.56 P>0.25),无统计学意义。结论局灶性灌注缺损伴有交叉性小脑神经联系不能可作为进展性卒中的早期影像诊断依据,具有临床应用价值。Objective To study the imaging features and clinical value of^99 mTc-ECD SPECT regional cerebral blood flow（ rCBF） imaging in stroke progression. Methods 61 patients with acute cerebral infarction were performed with99 mTcECD rCBF tomographic imaging within 24 hours of onset. All cases were performed with CT or MR. Patients were diagnosed as progressing stroke（ SP） and non-progressing stroke（ NPS） according to their decreased scores in Scandinavian stroke scale（ SSS） from baseline to the 1-week evaluation. Results SP group displayed various degree of decreased perfusion and crossed cerebellar diaschisis,but in NPS group,only 2 cases displayed crossed cerebellar diaschisis,the else only displayed decreased perfuson. Conclusion Decreased perfusion and diaschisis detectedat99 mTc-ECD SPECT in the early stage in patients with acute cerebral infarction indicates stroke progression.^99 mTc-ECD SPECT brain imaging has great clinical significnce and application value in patients with stroke progression.

关 键 词：进展性卒中 体层摄影术 单光子 发射型计算机 

分 类 号：R743.32[医药卫生—神经病学与精神病学]