肠道菌群改变与肝纤维化相互作用的研究进展  

Alterations in intestinal flora and hepatic fibrosis

作　　者：王蓉 宋明宇[2] 李学文 杜鹏 杨玲[3] 

机构地区：[1]长江航运总医院消化内科,湖北省武汉市430000 [2]华中科技大学同济医学院附属同济医院骨科,湖北省武汉市430000 [3]华中科技大学同济医学院附属协和医院消化内科,湖北省武汉市430022

出　　处：《世界华人消化杂志》2014年第26期3937-3940,共4页World Chinese Journal of Digestology

摘　　要：正常的肠道菌群对维持人体的健康起着重要的作用.当机体内外环境发生变化,产生肠道菌群失调时,会引起或加重机体多种疾病,特别是肝脏疾病.相反,肝纤维化发生时也可以引起或加重肠道菌群失调.机体肠道菌群的状况与肝纤维化进程关系密切、相互影响.本文主要探讨二者的关系,为临床提供新的治疗思路.The normal intestinal flora plays an important role in the maintenance of human health. When the internal and external environment of the body changes and there exists intestinal flora imbalance, a variety of diseases may develop, especially liver diseases. The existence of hepatic fibrosis can cause or aggravate intestinal flora imbalance. The status of the body＇s intestinal flora is closely related to liver fibrosis, and they can influence each other. This review mainly discusses the relationship between alterationsin intestinal flora and hepatic fibrosis to provide new clues to the therapy of this disease in clini- cal practice.

关 键 词：肠道菌群 肝纤维化 研究进展 

分 类 号：R575.2[医药卫生—消化系统]