香茅醛缩醛类化合物的合成及其对小黄家蚁的驱避活性  

Synthesis of acetal derivatives of citronellal and their repellent activities against the pharaoh ant,Monomorium pharaonis(Hymenoptera: Formicidae)

作　　者：翁玉辉[1] 肖转泉[2] 许锡招 陈金珠[3] 范国荣[1] 聂雪军[1] 王宗德[1] 

机构地区：[1]江西农业大学林学院国家林业局樟树工程技术研究中心,南昌330045 [2]江西师范大学化学化工学院,南昌330027 [3]江西农业大学理学院,南昌330045

出　　处：《昆虫学报》2014年第8期921-926,共6页Acta Entomologica Sinica

基　　金：国家林业公益性行业科研专项经费(201304602);江西省科技支撑计划课题(20132BBF60057);广西林产化学与工程重点实验室基金项目(GXFC11-07)

摘　　要：【目的】香茅醛类化合物具有较好的蚂蚁驱避活性,本研究旨在筛选具有良好驱避活性的新的萜类蚂蚁驱避剂。【方法】以香茅醛为原料合成了香茅醛二甲缩醛、香茅醛二乙缩醛、香茅醛二正丙缩醛、香茅醛二异丁缩醛、香茅醛乙二缩醛、香茅醛1,2-丙二缩醛和香茅醛1,3-丙二缩醛等化合物。所得产品经纯化后,用IR,MS,1H NMR及13C NMR进行结构表征,并在不同浓度下对小黄家蚁Monomorium pharaonis进行驱避活性测试。【结果】各化合物对小黄家蚁具有一定的驱避活性:在10 mg/mL的浓度下,除香茅醛二甲缩醛以外,其他化合物的驱避率均达到70%以上,其中香茅醛二乙缩醛、香茅醛乙二缩醛和香茅醛1,3-丙二缩醛对小黄家蚁的驱避率分别为87.47%,100%和97.53%。浓度为2.5 mg/mL时,其中5个化合物的驱避效果明显下降,但香茅醛乙二缩醛和香茅醛1,3-丙二缩醛仍然表现出很好的驱避活性,驱避率分别为85.33%和97.10%。方差分析也表明,香茅醛1,3-丙二缩醛在同一浓度下驱避效果最佳,其次是香茅醛乙二缩醛。【结论】结果说明,香茅醛二乙缩醛、香茅醛乙二缩醛和香茅醛1,3-丙二缩醛可以用作小黄家蚁驱避剂,而香茅醛乙二缩醛和香茅醛1,3-丙二缩醛可以达到更好的驱避效果,使用浓度为2.5 mg/mL即可。本研究为良好萜类蚂蚁驱避剂的筛选提供了参考依据。【Aim】Citronellal has good repellent activity against ants. This study aims to seek novel ant terpenoid repellents. 【Methods】 A series of citronella acetals including citronellal dimethyl acetal,citronellal diethyl acetal,citronellal dipropyl acetal,citronellal diisobutyl acetal,citronellal glycol acetal,citronellal 1,2-propanediol acetal and citronellal 1,3-propanediol acetal were synthesized in this study using citronellal as the starting material. Their structures were characterized with IR,MS,1H NMR and13 C NMR after purification. The repellent activities of these compounds at different concentrations against the pharaoh ant,Monomorium pharaonis were tested. 【Results】At the concentration of 10 mg /mL,all the compounds except citronellal dimethyl acetal had the repellent rate of more than 70%,and citronellal diethyl acetal,citronellal glycol acetal and citronellal 1,3-propanediol acetal had the repellent rates of 87. 47%,100% and 97. 53%,respectively. When the concentrations of the compounds dropped to 2. 5 mg /mL,the repellent activities of five compounds decreased significantly,while citronellal glycol acetal and citronellal 1,3-propanediol acetal still showed high repellent activities with the repellent rates of 85. 33% and 97. 10%,respectively. Variance analysis showed that citronellal 1,3-propanediol acetalhad the strongest repellent effect,followed by citronellal glycol acetal. 【Conclusion】The results suggest that citronellal diethyl acetal,citronellal glycol acetal and citronellal 1,3-propanediol acetal can be used for repelling M. pharaonis,and citronellal glycol acetal and citronellal 1,3-propanediol acetal can be better choices. This research provides a basic reference for screening good ant repellents.

关 键 词：香茅醛 缩醛类化合物 化学合成 结构表征 蚂蚁驱避剂 驱避活性 小黄家蚁 

分 类 号：Q965.9[生物学—昆虫学]