缺血再灌注过程中肝细胞自噬研究进展  

The role of the autophagy on liver cells under ischemia-reperfusion injury

作　　者：李静静[1] 郭传勇[1] 

机构地区：[1]同济大学医学院附属第十人民医院消化科,上海200072

出　　处：《胃肠病学和肝病学杂志》2014年第10期1117-1120,共4页Chinese Journal of Gastroenterology and Hepatology

基　　金：国家自然科学基金(81270515)

摘　　要：自噬(autophagy)是真核细胞进行代谢过程中特有的生命现象,在细胞存活与死亡中是把双刃剑,既能促进其存活也会导致细胞死亡,对于多种疾病的发展和治疗产生重要的影响。近来研究表明,自噬对于指导肝缺血再灌注损伤治疗的方法意义重大,为寻找其干预措施开拓了特殊的思路。As a peculiar phenomenon of eukaryotic cells,autophagy is a double-edged sword regarding to cell survival and death.It can not only protect cells but lead to death.For a variety of diseases,autophagy plays an important impact on the process and treatment of many diseases.Recent advances in the understanding of autophagy contributing to the treatment of liver ischemia-reperfusion injury have provided insight into opening a new way of thinking for the intervention measures.

关 键 词：肝细胞 缺血再灌注损伤 自噬 

分 类 号：R575[医药卫生—消化系统]