基于胃间质瘤CT形态学特征的病理危险度分级研究  

Relationship of CT features and pathological grades of malignancy in gastric stromal tumors

作　　者：高歌[1] 梁盼[1] 高剑波[1] 陈岩[1] 

机构地区：[1]郑州大学第一附属医院放射科,河南郑州450052

出　　处：《实用放射学杂志》2014年第10期1665-1669,共5页Journal of Practical Radiology

基　　金：河南省杰出青年计划项目（084100510020）.

摘　　要：目的：探讨多排螺旋CT形态学特征在评估胃间质瘤（GST）病理危险度分级中的价值。方法回顾分析本院80例经病理证实的 GST患者的临床及影像检查资料，根据病理组织学分为低危组、中危组、高危组。采用单因素方差分析各组间患者年龄、瘤体最大径及体积有无差异，采用Fisher’s精确检验分析各组间患者性别、肿瘤发生部位、生长方式、形态、边界、黏膜及浆膜情况、黏膜面溃疡情况是否有统计学差异。结果本组中低危组30例，中危组30例，高危组20例。GST的生长方式、形态、边界、浆膜、黏膜面溃疡情况及瘤体最大径、体积在各组间有统计学差异（P〈0.05），患者年龄、性别、肿瘤发生部位及黏膜情况在各组间无统计学差异（P〉0.05）。结论不同危险度组 GST的多排螺旋CT形态学特征具有差异，结合肿瘤大小、形态、生长方式、边界、浆膜及黏膜面溃疡等信息，有助于术前评估 GST危险度分级。Objective To study the relationship between the CT features and pathological grade of malignancy of the gastric stro-mal tumors （GST）.Methods A retrospective review was performed based on the database of 80 consecutive patients with GST.Age and gender of the patients were recorded,and the CT findings of GST including growth pattern,morphology,tumor site,boundary, mucosa,serosa,ulcer,volume and maximum diameter of the tumor were also measured.The patients were divided into three groups：very low and low risk group,intermediate risk one and high risk one according to the pathology.All parameters were ana-lyzed by one-way ANOVA or Fisher’s exact test.Results The patients in 3 groups （from low risk to high one）were 30,30 and 20 respectively.There were no significant differences in age,gender,location and mucosa among 3 groups（P〈0.05）.However,the growth pattern,morphology,boundary,serosa,ulcer,volume and maximum diameter of the tumor were significantly different （P〉0.05）.Conclusion The CT features including growth pattern,morphology,boundary,serosa,ulcer,volume and maximum diameter of the tumor can be used to evaluate the grades of malignancy in GST.

关 键 词：胃肠道间质肿瘤 计算机体层成像 

分 类 号：R735.2[医药卫生—肿瘤] R814.42[医药卫生—临床医学]