负压吸引对角膜影响在角膜地形图上表现研究  

Exprimental study of the influence of negative suction to cornea in the performance of corneal topographic map

作　　者：刘育霞[1] 王平[1] 

机构地区：[1]潍坊医学院附属医院眼科,山东潍坊261031

出　　处：《中国实用眼科杂志》2014年第10期1246-1248,共3页Chinese Journal of Practical Ophthalmology

摘　　要：目的 通过准分子激光手术负压吸引眼压瞬时升高时角膜地形图的变化,探讨负压吸引高眼压对角膜的影响.方法 实验研究.选取新西兰大白兔48只（96只眼）,按数字法随机分为2组,氯氨酮麻醉后角膜地形图检查,一组负压吸引30 s,另一组负压吸引60 s后,即刻、吸引后4h、1d、1周分别行角膜地形图检查,记录结果并进行统计学分析.结果 两组96只眼均在负压吸引30s、60 s后即刻及吸引后4h发生角膜前、后表面高度增加,曲率变大,角膜中央变厚,角膜直径扩大差异有统计学意义（P＜0.05）.至吸引后1d角膜地形图表现恢复至吸引前,1周时角膜地形图表现与1d时比较无明显变化,差异无统计学意义（P＞0.05）.结论 LASIK负压吸引形成的瞬时高眼压导致角膜前凸,曲率变大,角膜中央变厚,角膜直径扩大;但变化是可逆的,均在吸引后1d恢复正常.Objective To discuss the effect of high intraocular pressure to comea after negative pressure suction through the change of corneal topographic map at transiently elevated intraocular pressure of excimer laser operation negative pressure suction.Methods Forty-eight New Zealand big white rabbits（96 eyes）were selected and divided into 2 groups randomly for corneal topographic map examination after ketamine anesthesia.Negative pressure suction 30 seconds in the first group,and 60 seconds in the other group.For corneal topographic map examination at the times of immediate,4 hours,1 day,1 week after negative suction.The results were recorded and statistical analyzed.Results The height and curvature increased at the front and rear surfaces of corneal,corneal central thickened,and diameter enlarged at the times of immediate and 4 hours after suction in the two groups.The corneal topographic map returned to normal at the time of 1 day after suction.There weren＆#39;t obvious changes at the comeal topographic map at the time of 1 week after suction.Conclusions The transient high intraocular pressure after LASIK negative pressure suction lead to comeal prognathism,curvature increase,corneal central thicken,and diameter enlarge.But the changes are reversible,and return to normal at 1 day after suction.

关 键 词：负压吸引 角膜 角膜地形图 

分 类 号：R779.63[医药卫生—眼科]