大剂量热碘油TACE联合射频消融术治疗消化道癌肝转移  

Large dose heat lipiodol TACE combined with radiofrequency ablation in treatment of hepatic metastases of digestive tract cancer

作　　者：独建库[1] 张明德[1] 邹洋[1] 马小桔[1] 

机构地区：[1]解放军第150医院介入科,河南洛阳471031

出　　处：《临床军医杂志》2014年第9期898-900,共3页Clinical Journal of Medical Officers

摘　　要：目的评价大剂量热碘油肝动脉化疗栓塞术(TACE)联合射频消融术(RFA)治疗消化道癌肝转移的临床疗效。方法将96例消化道癌肝转移患者分为两组,48例(联合组)采用大剂量热碘油TACE联合RFA治疗;48例(对照组)采用常温碘油TACE治疗。结果联合组有效率为75%(36/48),对照组有效率为33%(16/48),两组间差异有统计学意义。两组术后肝功能变化无统计学意义。术后6、12、18、24个月生存率联合组分别为100%、85%、56%、27%,对照组分别为90%、53%、19%、8%。结论大剂量热碘油TACE联合RFA可以有效控制肝转移癌患者肝内病变的进展,延长患者生存期,而肝功能无明显的损害。Objective To study the clinic effects of large dose heat lipiodol transcatheter arterial chemoembolization （TACE） com- bined with radiofrequency ablation （RFA） in the treatment of hepatic metastases of digestive tract. Methods A total of 96 patients with hepatic metastases of digestive tract cancer were divided into two groups. Trial group （ n = 48 ） was treated by large dose heat lipiodol TACE combined with RFA and control group （ n = 48 ） treated by normal temperature lipiodol TACE. Results Effective rate was 75% （36/48） in the trial group and 33% （16/48） in the control group, between which there was a statistically signifi- cant difference. The changes in liver function after operation were of no statistically significant difference between the two groups. Postoperative survival rates of 6, ]2, 18 and 24 months were 100% , 85% , 56% and 27% in the trial group and 90% , 53% , 19% and 8% in the control group, respectively. Conclusion large dose heat lipiodol TACE plus RFA helps to control the patho- logical development inside liver in the patients with hepatic metastasis and therefore prolong their survival period without obvious damage to liver function.

关 键 词：消化道肿瘤 肝转移癌 热碘油 射频消融术 

分 类 号：R735[医药卫生—肿瘤]