饮茶与男性脑出血发病风险的研究  

A prospective cohort study of tea consumption and risk of cerebral hemorrhage in males

作　　者：孟令民[1] 陈朔华[2] 朱颖[2] 韩红锋[2] 吴寿岭[2] 

机构地区：[1]河北联合大学附属开滦总医院急诊科,河北唐山063000 [2]河北联合大学附属开滦总医院心内科,河北唐山063000

出　　处：《中华高血压杂志》2014年第9期836-840,共5页Chinese Journal of Hypertension

摘　　要：目的探讨饮茶对男性脑出血发病风险的影响。方法采用前瞻性队列研究方法,以2006年7月至2007年10月参加健康体检的开滦集团在职及离退休男性职工76 864人作为观察队列,根据健康问卷中的饮茶频率分为从不饮茶（n=50 180）、偶尔饮茶（n=11 834）、经常饮茶（n=14 850）3组,平均随访4.03年,Cox回归模型分析饮茶频率对男性脑出血发病的影响。结果从不饮茶组的脑出血发病率高于偶尔及经常饮茶组[1.41/1000人年比0.61/1000人年,0.90/1000人年,P〈0.01]。校正年龄、血压和高血压病史后,多因素Cox回归模型显示,从不、偶尔及经常饮茶组的脑出血的风险比（95%CI）分别为1.00、0.59（0.40-0.87）、0.66（0.49-0.88）,均P〈0.01。结论适度饮茶可以降低男性脑出血的发病风险。Objective To assess the association between tea consumption and the risk of cerebral hemorrhage in males. Methods A total of 76 864 male in-service employees and retirees of the Kailuan Group who participated in health examination from July 2006 to October 2007 were recruited with an average 4.03 years follow-up. According to the frequency of tea consumption, the participants were classified into 3 groups： the never （n= 50 180）, occasional （n= 11 834）, and regular tea-drinking groups （n = 14 850）. A multivariable Cox proportional hazards regression model was used to assess the association between the frequency of tea consumption and the risk of cerebral hemorrhage. Results The incidence of cerebral hemorrhage （per 1000 person-years） was 1.41 （286/202 137）, 0.61 （29/47 703） , and 0.90 （54/60 163} in the never, occasional, and regular tea-drinking groups, the differences being statistically significant （P〈0. 01 ）. After adjusting for age, blood pressures and history of hypertension, the hazard ratios of cerebral hemorrhage associated with different levels of tea consumption ]-never （reference group）, occasional and regular tea-drinking] were 1.00, 0.59 （950/00 CI 0. 40-0.87）, and 0.66 （95G CI 0. 49-0.88}, respectively. Conclusion Moderate consumption of tea could reduce the risk of cerebral hemorrhage in males.

关 键 词：饮茶 脑出血 前瞻性队列研究 

分 类 号：R743[医药卫生—神经病学与精神病学]