松果体区表皮样囊肿的临床、影像学和病理学特点  

Clinical, radiological and pathological features of the pineal epidermoid cysts

作　　者：袁辉胜[1] 张红波[1] 穆林森[2] 李储忠[3] 桂松柏[3] 孙彦辉[3] 宗绪毅[3] 张亚卓[3] 

机构地区：[1]湖北省新华医院神经外科,武汉430015 [2]广州市脑科医院神经外科,广州510170 [3]首都医科大学北京天坛医院神经外科,北京100050

出　　处：《中国临床神经外科杂志》2014年第10期596-598,共3页Chinese Journal of Clinical Neurosurgery

摘　　要：目的探讨松果体区表皮样囊肿的临床、影像学和病理学特点。方法回顾性分析手术治疗的5例松果体区表皮样囊肿患者的临床资料。结果 CT平扫呈均匀一致似脑脊液样低或等密度病灶,形态不规则,沿脑池生长。MRI T1WI为不均匀低信号,T2WI为不均匀高信号,病变呈分叶状,边界清楚,囊内容物及囊壁均未见明显强化。病理表现为珍珠样颗粒结晶,囊内含较多蛋白、脂类物质、胆固醇结晶。5例松果体区表皮样囊肿中,4例全切,1例近全切。术后随访3~12个月,平均5.8月,肿瘤无复发。结论松果体区表皮样囊肿临床少见,全切预后较好。Objective To analyze the clinical, radiological and pathological features of epidermoid cyst of the pineal region （ECPR）. Methods The retrospective analysis of the clinical data of 5 patients with ECPR, who underwent surgery from January, 2010 to September, 2012 was made and the literatures related to the ECPR were reviewed. Results Of 5 patients ECPR, 4 underwent total resection and 1 subtotal. The Pathological examination showed that the tumor seemed to be Pearl crystal and there were more protein, lipids, cholesterol crystal within the cysts. The cerebrospinal fluid-like uniform low or equal density lesions with irregular shape growing along the cerebral cistern appeared on CT image of the cysts. The inhomogeneous low signal appeared on MR T^WI and the inhomogeneous high signal appeared on MR T2WI. The cysts were lobular in shape and had clear boundary on MRI. Enhanced MRI scanning showed that there was no obvious enhancement of cystic contents and walls. The following up from 3 to 12 months （mean, 5.8 months） showed that no cysts recurred in all the patients. Conclusions ECPR is rare. The curative effect of total removal of the cyst by surgery on ECPR is good. The diagnosis of ECPR may be easily made by the clinical manifestation, imaging and pathology.

关 键 词：松果体区表皮样囊肿 病理学 影像学 

分 类 号：R739.41[医药卫生—肿瘤] R651.11[医药卫生—临床医学]