急性心肌梗死患者白细胞计数与心律失常发生率的相关性分析  

Analysis on the Correlation between White Blood Count and Incidence Rates of Arrhythmia in Patients with Acute Myocardial Infarction

作　　者：罗莘 

机构地区：[1]株洲市恺德心血管病医院心内科,湖南株洲412002

出　　处：《医学综述》2014年第21期3994-3995,共2页Medical Recapitulate

摘　　要：目的 探讨急性心肌梗死（AMI）患者白细胞计数与心律失常发生率的相关性.方法 选取2009年4月至2012年5月株洲市恺德心血管病医院收治的203例AMI患者作为研究对象,依据白细胞计数结果将患者分为三组：A组（白细胞计数＜8.0 ×10^9L^-1）45例,B组（白细胞计数8.0×10^9L^-1～16.0×10^9L^-1）109例,C组（白细胞计数＞16.0×10^9L^-1）49例.分析上述三组患者血清心肌肌钙蛋白I（cTnI）、肌酸激酶MB同工酶（CK-MB）的检测结果,以及各组患者心律失常的发生率.结果 C组患者血清cTnI、CK-MB水平显著高于B组（P＜0.05）,B组患者血清cTnI、CK-MB水平显著高于A组（P＜0.05）.C组患者窦性心动过速、心房颤动、室性期前收缩、室性心动过速、心室颤动、房室传导阻滞、束支传导阻滞的发生率显著高于B组（P＜0.05）,B组患者上述类型心律失常的发生率显著高于A组（P＜0.05）,且AMI患者白细胞计数与上述类型心律失常的发生率呈正相关（P＜0.05）.结论 AMI患者白细胞计数与多数类型心律失常的发生率呈正相关,临床应重视AMI患者白细胞升高的检测.Objective To explore the correlation between the white blood count （WBC） and incidence rates of arrhythmia in patients with acute myocardial infarction （AMI）. Methods A total of 203 cases of patients with AMI admitted in Kaide Cardiovascular Disease Hospital from Apr. 2009 to May 2012 were selected and divided into 3 groups according to WBC ：45 cases as group A （ WBC 〈 8.0 ×10^9L^-1）, 109 cases as group B（（8.0-16.0） ×10^9L^-1 〈 WBC 〈 16.0 ×10^9L^-1 ） and 49 cases as group C（ WBC 〉 16.0×10^9L^-1） ,respectively. The levels of serum cardiac troponin 1 （cTnl） and creatine kinase MB isoenzyme （ CK-MB）, as well as the incidence rates of arrhythmia of the 3 groups were analyzed retrospectively. Results The levels of serum cTnl and CK-MB of group C were significantly higher than those of group B （P 〈 0.05 ）, and such levels of group B were significantly higher than those of group A （ P 〈 0.05 ）. The incidence rates of sinus tachycardia, atrial fibrillation, premature ventricular beats, ventricular tachycardia, ventricular fibrillation, atrioventrieular block,bundle branch block of group C were significantly higher than those of group B （ P 〈 0.05 ）, and such rates of group B were significantly higher than those of group A （ P 〈 0.05 ）. WBC of AMI patients was positively correlated with the incidence rates of those types of arrhythmia mentioned above （P 〈 0.05）. Conclusion There is a positive correlation between WBC and most types of arrhythmia in patients with AMI, so AMI patients with leukocytnsis should be paid more attention to in clinical practice.

关 键 词：急性心肌梗死 白细胞 心律失常 心肌肌钙蛋白I 肌酸激酶MB同工酶 

分 类 号：R743[医药卫生—神经病学与精神病学]