LASIK非球面切削治疗近视眼术后3年角膜Q值及曲率变化  

The variation of cornea Q-value and curvatures in three years after receiving aspheric LASIK for treatment of myopia

作　　者：陈章明[1] 赵婷婷[1] 黄丹[1] 

机构地区：[1]哈尔滨242医院眼科,150066

出　　处：《眼科》2014年第5期301-304,共4页Ophthalmology in China

摘　　要：目的 比较准分子激光原位角膜磨镶术（LASIK）非球面切削及普通切削术后3年的角膜Q值及曲率变化。设计回顾性比较性病例系列。研究对象哈尔滨242医院行准分子激光近视治疗的患者155例（295眼）。方法 患者分非球面切削和普通切削两组,每组预留基质分为〉350μm（A组）、300～350μm（B组）及280～299μm（C组）三组。不同术式两组患者术前年龄、等效球镜度数、中央角膜厚度无统计学差异。利用Orbscan II检测术后1周,1、6个月,1、3年角膜Q值及前表面曲率。主要指标角膜Q值及前表面曲率。结果 手术后3年时,非球面切削者三组角膜Q值分别是A组0.27±0.21、B组0.33±0.31、C组0.93±0.19;角膜前表面曲率分别是（39.6±1.17）D、（39.9±0.83）D、（37.9±1.51）D。普通切削者三组的角膜Q值分别是A组0.35±0.24、B组0.71±0.35、C组1.03±0.36;角膜前表面曲率分别是（40.2±0.98）D、（39.6±0.33）D、（37.3±1.83）D,差异无统计学意义。结论 经过3年的观察显示,与LASIK普通切削模式相比,非球面切削在预留基质300～350μm范围内能保持更好的角膜非球面形态。两组术式在预留基质280μm以上时均是安全的。Objective To compare the variation of cornea Q -value and curvatures in three years after receiving aspheric LASIK or LASIK for a treatment of myopia. Design A retrospective comparative case series. Participants 155 patients （295 eyes） who underwent LASIK in Haerbin 242 hospital were chosen to participate in current study. Methods Patients were divided into two groups, aspheric LASIK group and conventional LASIK group. According to the corneal matrix reservation, each group were divided into three subgroups： group A〉350 μm, group B 300-350μm and group C 280～299 μm. Q-value and anterior cornea curvatures were measured with Orbscan II topography system before and 1 week, 1 month,6 month, 1 year, 3 year after surgery. Main Outcome Measures The Q-value and anterior cornea curvatures. Results At the third year after surgery, the Q-value of patients who received aspheric LASIK group was group A 0.27±0.21, group B 0.33±0.31 and group C 0.93±0.19 respectively. The anterior cornea curvatures of the three groups was 39.6±1.17 D, 39.9±0.83 D and 0.93±0.19 D respectively. In the LASIK group, the Q-value was group A 0.35±0.24, group B 0.71±0.35 and group C 1.03±0.36 respectively. The anterior cornea curvatures was 40.2±0.98 D, 39.6±0.33 D and 37.3±1.83 D respectively, and the difference was not significant. Conclusion After 3 years＇ follow-up, aspheric profile could maintain the corneal aspherical shape better than conventional LASIK when the corneal matrix reservation was 300-350 μm. When the corneal matrix reservation was greater than 280 μm, both of these surgeries were safe.

关 键 词：准分子激光原位角膜磨镶术 非球面 Q值 角膜曲率 

分 类 号：R779.63[医药卫生—眼科]