脑卒中并发肺部感染病原菌分布及耐药性分析  

Distribution and drug resistance of pathogens from stroke patients with pulmonary infection

作　　者：曾宗鼎[1] 王景[2] 何超明[2] 

机构地区：[1]海南省农垦三亚医院呼吸内科,海南三亚572000 [2]海南省农垦三亚医院神经内科,海南三亚572000

出　　处：《临床肺科杂志》2014年第12期2145-2147,共3页Journal of Clinical Pulmonary Medicine

基　　金：三亚市医疗卫生科技创新项目(No YW1216)

摘　　要：目的：探讨脑卒中并发肺部感染患者的病原菌分布及耐药状况。方法对2013年3月～2014年3月收住我院的118例脑卒中伴发肺部感染患者的痰培养和药敏试验结果进行分析。结果痰培养共检出菌株147株，以革兰阴性杆菌为主（66．7%），其次为革兰阳性球菌（19．0%）和真菌（14．3%）。革兰阴性杆菌以铜绿假单胞菌为主，对亚胺培南最敏感；革兰阳性球菌主要是金黄色葡萄球菌，对万古霉素最敏感；真菌以白色假丝酵母菌为主，对氟康唑最敏感。结论革兰阴性杆菌是脑卒中并发肺部感染的主要病原菌，临床应及时进行细菌培养及耐药性检测，根据药敏试验结果选择抗菌药物。Objective To investigate the distribution and the drug resistance of pathogens from stroke pa-tients with pulmonary infection. Methods The results of sputum culture and drug susceptibility tests from 118 stroke patients were analyzed. Results 147 strains were detected in sputum culture, and gram-negative bacilli occupied 66. 7%, followed by gram-positive cocci （19. 0%） and fungi （14. 3%）. In gram-negative bacteria, the most com-mon pathogen was pseudomonas aeruginosa and sensitive to mipenem. In gram-positive bacteria, the most common pathogen was staphylococcus aureus and sensitive to vancomycin. In fungi, the most common pathogen was candida albicans and sensitive to fluconazole. Conclusion Gram-negative bacteria are the dominant pathogens in pulmonary infection pathogens. Bacterial culture and drug resistance tests should be timely given to guide the use of antibiotics.

关 键 词：脑卒中 肺部感染 病原菌 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R446.5[医药卫生—临床医学]