丹参注射液联合生长抑素治疗急性胰腺炎疗效分析及对血淀粉酶的影响  

Salvia Miltiorrhiza Injection Combined with Somatostatin in Treatment of Acute Pancreatitis and Its Effects on Blood Amylase

作　　者：方欢欢 杨河 丁毅[2] 

机构地区：[1]奉化市人民医院消化科,浙江奉化315500 [2]宁波市医疗中心李惠利医院ICU,浙江宁波315040

出　　处：《中华中医药学刊》2014年第11期2811-2813,共3页Chinese Archives of Traditional Chinese Medicine

摘　　要：目的:探讨丹参注射液联合生长抑素治疗急性胰腺炎疗效及对血淀粉酶的影响,为临床诊断治疗提供参考。方法:110例急性胰腺炎患者根据随机数字表法随机分为观察组(n=55)和对照组(n=55)。对照组给予生长抑素治疗;观察组在对照组治疗基础上给予丹参注射液治疗。结果:观察组治疗后总有效率(89.19%)显著高于对照组(74.55%),且有显著性差异(P<0.05);观察组治疗后3、6、9 d血淀粉酶显著低于对照组,且有显著性差异(P<0.05);观察组治疗后血淀粉酶恢复及腹部症状改善时间明显短于对照组,且差异具有统计学意义(P<0.05);观察组治疗后3、6、9 d血钙显著高于对照组,且有显著性差异(P<0.05);观察组治疗后并发症发生率和住院时间均显著低于对照组,且差异具有统计学意义(P<0.05)。结论:丹参注射液联合生长抑素治疗急性胰腺炎疗效显著,可明显降低血淀粉酶,降低并发症,缩短住院时间,临床应用具有重要研究价值。Objective：To investigate the combined effect of Salvia Injection combined with somatostatin in the treatment of acute pancreatitis and its effect on serum amylase and to provide reference for clinical diagnosis and treatment. Methods： 110 cases of acute pancreatitis were randomly divided into two groups according to the random number table：observation group （ n = 55 ） and control group （ n = 55 ）. The control group received somatostatin therapy and the observation group combined Salvia Injection. Results： The total effective rate （89.19%） in observation group was significantly higher than that of control group （74.55%） after treatment and there was significant difference （P 〈 0.05 ）. In observation group 3d,6d,9d after treatment, serum amylase was significantly lower than that of the control group （ P 〈 0.05）. In observation group, blood amylase recovery and abdominal symptoms improved time significantly were shorter than those of the control group and the difference was statistically significant （ P 〈 0. 05 ）. In observation group 3 d, 6 d, 9 d after treat- ment, blood calcium was significantly higher than that of the control group and there were significant differences （ P 〈 0. 05）. In observation group after treatment, the morbidity and hospital stay were significantly lower than those of the control group and the difference was statistically significant （ P 〈 0. 05 ）. Conclusion ： Salvia injection combined with somatostatin treatment of acute pancreatitis significant has obvious effect and can significantly reduce blood amylase, reduce complications, shorten hospital stays. Its clinical applications have important research value.

关 键 词：丹参注射液 生长抑素 急性胰腺炎 疗效 血淀粉酶 

分 类 号：R576[医药卫生—消化系统]