有氧运动对改善首发精神分裂症患者认知与社会功能的疗效观察  

Clinical observation ofaerobics improving cognitive and social function of patients with first-episode schizophrenia

作　　者：张肃[1] 倪晓梅[2] 张新安[1] 

机构地区：[1]沈阳体育学院运动人体科学学院,辽宁沈阳110102 [2]沈阳市精神卫生中心,辽宁沈阳110168

出　　处：《中国现代医学杂志》2014年第30期71-75,共5页China Journal of Modern Medicine

基　　金：沈阳市科学技术计划项目(No:F11-262-9-26);辽宁省科学技术计划项目(No:2013231001)

摘　　要：目的观察有氧运动干预在改善首发精神分裂症患者认知与社会功能的疗效。方法入选本院2010年2月-2013年1月首发精神分裂症患者80例,根据随机数字表分为观察组(n=43例)与对照组(n=37例),对照组患者住院期间主要予利培酮药物疗法,观察组在此基础上给予规律性有氧运动干预,每日活动1 h,对比两组患者出院前认知功能与社会功能改善情况。结果 1两组患者出院前认知功能各项指标均较之入院明显改善;观察组患者干预后在认知评价中正确应答数(68.8±10.7)、错误应答数(38.5±12.8)、持续错误数(26.5±10.2)、概念化水平百分比(79.6±13.1)得分均优于对照组(64.3±9.2)、(46.2±11.6)、(34.3±9.1)、(73.4±12.0),差异具有显著性(P<0.05)。2两组患者干预前后社会功能评分较之干预前明显改善;观察组干预后在工疗情况(7.1±2.9)、生活能力(6.6±2.5)、社交能力(3.8±1.4)及总分(29.7±5.7)方面显著优于对照组水平(9.0±3.2)、(7.8±2.7)、(5.1±1.7)、(34.9±6.6),差异有显著性(P<0.05)。结论对首发精神分裂症患者常规药物治疗基础上结合适当的有氧运动干预,有助于改善患者心境,提高其认知与社会功能。【Objective】To observe the curative effect about the aerobics exercise to improve the cognitive and social function on patients with first-episode schizophrenia.【Methods】80 admitted first-episode schizophrenia cases of Feb 2010~Jan 2013 were randomly divided into observation group（n =43 cases） and control group（n =37 cases）according to the random number table, control group was treated with risperidone oral therapy in hospital, based on which observation group was given regular aerobic exercise intervention 1 h/d, and cognitive social function of 2groups were compared before discharge. 【Results】Two groups before discharge whose cognitive function indexes were significantly improved compared with pre-treatment. Observation group whose correct responses score（68.8±10.7）, error responses score（38.5±12.8）, number of perseverative errors score（26.5±10.2）, conceptual level percentage scores（79.6±13.1） were better than control group（64.3±9.2）,（46.2±11.6）,（34.3±9.1）,（73.4±12）, the difference were statistically significant（P〈0.05）. Two groups after intervention whose social function score were both better than pre-treatment; observation group whose occupational situation sore（7.1±2.9）, living ability score（6.6±2.5）, social ability score（3.8±1.4） and aggregate score（29.7±5.7） were better than control group（9.0±3.2）,（7.8±2.7）,（5.1±1.7）,（34.9±6.6）, the difference were statistically significant（P〈0.05）.【Conclusions】Based on routine drug therapy, first-episode schizophrenia patients with applying regular aerobic exercise intervention can help to improve psychological states and cognition social function.

关 键 词：首发精神分裂症 有氧运动干预 认知功能 社会功能 疗效 

分 类 号：R749.3[医药卫生—神经病学与精神病学]