两种口服复方聚乙二醇电解质散清洁肠道方法的临床观察  

Clinical Observation of 2 Kinds of Oral Compound Polyethylene Glycol-electrolyte Powder for Bowel Cleaning

作　　者：赵晋炜 杨阿罗[1] 张勇[1] 倪海燕[1] 

机构地区：[1]山西省肿瘤医院,太原030013

出　　处：《中国药房》2014年第44期4177-4178,共2页China Pharmacy

摘　　要：目的:观察两种口服复方聚乙二醇电解质散清洁肠道方法的效果和安全性。方法:将243例行结肠镜检查的患者随机分为观察组(127例)和对照组(116例)。观察组患者检查前一日晚口服酚酞片0.6 g,检查当日术前4 h服用2袋复方聚乙二醇电解质散(69.56 g/袋);对照组患者检查前一日晚及检查当日术前4 h各服用1袋复方聚乙二醇电解质散。比较两组患者的肠道清洁效果、排便次数和不良反应发生率。结果:两组患者肠道准备合格率差异无统计学意义(P>0.05);对照组患者肠道准备过程中的排便次数显著多于观察组,两组比较差异有统计学意义(P<0.05);对照组患者的不良反应发生率显著高于观察组,两组比较差异有统计学意义(P<0.05)。结论:观察组患者所采用的口服复方聚乙二醇电解质散清洁肠道方法效果较好,对检查前一日夜间睡眠影响小,且安全性较好。OBJECTIVE： To observe therapeutic efficacy and security of 2 kinds of oral Compound polyethylene glycol-electro- lyte powder for bowel cleaning. METHODS ： 243 patients underwent colonoscopy were randomized into observation group （ 127 patients） and control group （116 patients）. Observation group received Phenolphthalein tablet 0.6 g orally at night before examination, and 2 bags of Compound polyethylene glycol-electrolyte powder （69.56 g/bag） 4 h before surgery. Control group was given one bag of Compound polyethylene glycol-electrolyte powder at night before examination and 4 h before surgery. The degree of bowel cleanness, defecation times and the incidence of ADR were compared between 2 groups. RESULTS： There was no statistical significance in qualification rate of bowel preparation between 2 groups （P〉0.05）. The defecation times of control group was significantly higher than that of observation group; there was statistical significance （P〈0.05）. The incidence of ADR in control group was significantly higher than in observation group; there was statistical significance （P〈0.05）. CONCLUSIONS： The oral Compound polyethylene glycol-electrolyte powder can provide better bowel cleanness for the observation group, having less impact on the patients in their sleep and more security.

关 键 词：复方聚乙二醇电解质散 清洁肠道 效果 安全性 

分 类 号：R574[医药卫生—消化系统] R981[医药卫生—内科学]