柠檬酸镁溶液联合复方聚乙二醇电解质散在结肠镜检查前肠道准备中的效果观察  

Effect observation on magnesium citrate combined with compound polyethylene glycol electrolyte powder in bowel preparation before eolonoscopy

作　　者：杨光[1] 宋林繁 王勇[1] 沈海峰[1] 范亚召 

机构地区：[1]河北省衡水市第四人民医院肛肠外科,053000

出　　处：《中国医师进修杂志》2014年第32期49-51,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的探讨柠檬酸镁溶液联合复方聚乙二醇电解质散在结肠镜检查前肠道准备中的临床效果。方法将106例因下消化道症状等行结肠镜检查患者按随机数字表法分为研究组（54例）和对照组（52例），研究组应用柠檬酸镁溶液联合复方聚乙二醇电解质散进行肠道准备，对照组应用复方聚乙二醇电解质散进行肠道准备。比较两组病变检出情况、肠道准备质量、首次排便时间、排便次数、进镜时间、服用肠道准备药物后电解质及肝肾功能以及不良反应等。结果两组病变检查率、进镜时间、服用肠道准备药物后电解质及肝肾功能比较差异无统计学意义（P〉0．05）。研究组肠道准备质量总有效率明显高于对照组[96．3％（52／54）比82．7％（43／52）]，首次排便时间明显短于对照组[（32.5±26．1）min比（47．2±22．4）min]，排便次数明显多于对照组[（8．2±2．9）次比（6．2±2．6）次]，差异有统计学意义（P〈0．05）。研究组恶心发生率明显低于对照组[22．2％（12／54）比48．1％（25／52）]，差异有统计学意义（P〈0．05）；两组呕吐、腹胀、腹痛发生率比较差异无统计学意义（P〉0．05）。结论柠檬酸镁联合复方聚乙二醇电解质散应用于结肠镜检查的术前肠道准备可提高肠道准备质量，减少并发症的发生。Objective To study the effect of magnesium citrate combined with compound polyethylene glycol electrolyte powder in bowel preparation before colonoscopy. Methods One hundred and six colonoscopy patients with lower digestive tract symptom were divided into study group （54 cases） and control group （52 cases） by random digits table method, the bowel preparation in study group was magnesium citrate combined with compound polyethylene glycol electrolyte powder, in control group was compound polyethylene glycol electrolyte powder. The lesions detection rate, bowel preparation quality, time of first defecation, number of defecation, time of eolonoseopy, results of the electrolyte level and liver and kidney function after medication and adverse reaction were compared between two groups. Results There were no statistical differences in lesions detection rate, time of colonoscopy, results of the electrolyte level and liver and kidney function after medication between two groups （P 〉 0.05）. The total effective rate of bowel preparation quality in study group was significantly higher than that in control group [96.3% （52/54） vs. 82.7% （43/52）], the time of first defecation was significantly shorter than that in control group [ （32.5 ± 26.1 ） rain vs. （47.2 ± 22.4 ） rain ], the number of defecation was significantly much than that in control group [ （8.2 ± 2.9） times vs. （6.2 ± 2.6） times],there were statistical differences （P〈 0.05）. The incidence of nausea in study group was significantly lower than that in control group [ 22.2% （12/54） vs. 48.1% （25/52）] ,there was statistical difference （P 〈 0.05）. There were no statistical differences in the incidences of vomiting, abdominal distention and abdominal pain between two groups （P 〉 0.05）. Conclusion Magnesium citrate combined with compound polyethylene glycol electrolyte powder used in preoperative bowel preparation for colonoseopy has better clinical application value.

关 键 词：结肠镜 柠檬酸镁 复方聚乙二醇电解质散 肠道准备 

分 类 号：R574[医药卫生—消化系统]