磁共振技术在急性缺血性卒中出血转化预测中的应用  

Prediction of Hemorrhagic Transformation in Acute Ischemic Stroke Using Magnetic Resonance Imaging

作　　者：金信春 楼敏[1] 

机构地区：[1]浙江大学附属第二医院神经内科,杭州310009

出　　处：《中国卒中杂志》2014年第11期936-941,共6页Chinese Journal of Stroke

摘　　要：出血转化(hemorrhagic transformation,HT)是缺血性卒中最严重的并发症之一。近年来,随着技术的发展,磁共振能较准确地反映HT的生理机制,例如通过弥散加权技术反映细胞的代谢障碍,灌注加权技术反映组织的灌注缺损,血脑屏障通透性技术反映血脑屏障破坏程度,进而在此基础上评估HT的风险。本文将对磁共振技术在预测缺血性卒中发生HT的应用及进展做一综述。Hemorrhagic transformation （HT） is one of the most critical complications of acute ischemic stroke. Recently, magnetic resonance imaging （MRI） can be used to accurately reflect the physiological mechanism of HT, such as diffusion weighted imaging can be used to reflect the metabolic disturbances of brain cells, perfusion weighted imaging can be used to reflect the perfusion defects of brain tissue, and blood-brain barrier permeability imaging can be used to reflect the destruction of the blood brain barrier, thus helping to assess the risk of liT. This review is focused on current knowledge regarding the application and progress of MR/for predicting HT.

关 键 词：出血转化 急性缺血性卒中 磁共振 血脑屏障 预测 

分 类 号：R743.3[医药卫生—神经病学与精神病学]