老年高血压患者血压变异性与认知功能损害的相关性研究  

Correlation between blood pressure variability in elderly hypertensive patients with cognitive impairment

作　　者：程文静[1,2] 闫中瑞[2] 

机构地区：[1]济南大学山东省医学科学院医学与生命科学学院,山东济南250000 [2]山东省医学科学院附属济宁市第一人民医院,山东济宁272011

出　　处：《世界最新医学信息文摘》2014年第29期81-82,共2页World Latest Medicine Information Electronic Version

摘　　要：目的探讨老年高血压患者血压变异性与认知功能损害的关系。方法选择老年高血压患者国际通用的简易智力状况量表（M M SE）进行评定，根据评分结果分为认知障碍组和正常组，对所有研究对象进行24h动态血压监测。结果认知障碍组24h、昼间及夜间平均收缩压明显高于正常组。认知障碍组24h收缩压标准差（24hSSD）、昼间收缩压标准差（dSSD）及24小时收缩压加权标准差（24hSwSD）显著高于正常组。结论老年高血压患者认知障碍的发病率与血压变异性密切相关。Objective To explore the relationship between blood pressure variability and cognitive impairment in elderly hypertensive patients. Methods the cognitive function of elderly patients with hypertension were assessed according to the international generally used mini-mental state examination （MMSE）. then the patients were divided into cognitive impairment group and normal group in accordance with the score results, and their ambulatory blood pressure were monitored for 24 h in all the research subjects.Results the average systolic blood pressure in24h, daytime and nighttime in cognitive impairment group, were significantly higher than that in the normal group. The 24h systolic blood pressure standard deviation （24hSSD）, daytime systolic blood pressure standard deviation （dSSD） and 24h systolic blood pressure weighted standard deviation （24hswsd） were significantly higher than that in the normal group.Conclusion the incidence of cognitive impairment in elderly hypertension patients is closely related to blood pressure variability.

关 键 词：高血压 认知功能损害 血压变异性 

分 类 号：R74[医药卫生—神经病学与精神病学]