应用SPECT分子影像技术评价HANS治疗儿童孤独症的价值  

THE ANALYSIS OF THE THERAPUTIC EFFECT OF HANS ON CHILDHOOD AUTISM WITH SPECT MOLECULAR IMAGING TECHNOLOGY

作　　者：孙雯[1] 杨红杰[1] 贾少微[1] 张嘉辉[1] 赵正勤[1] 

机构地区：[1]北京大学深圳医院核医学科,深圳518036

出　　处：《中国疼痛医学杂志》2014年第10期713-716,共4页Chinese Journal of Pain Medicine

基　　金：国家中医药科学技术研究基金项目(编号:00-01LP11);深圳市科技计划项目医疗卫生类(编号:201102015)

摘　　要：目的:应用SPECT分子影像技术评价HANS治疗儿童孤独症(childhood Autism,CA)的价值。方法:回顾性调查分析能坚持HANS治疗≥12个月的39例CA患儿。使用HANS 100A或200A型神经穴位刺激仪,选择肢体穴位组合,每天治疗2次共2小时。分别在HANS治疗前后进行2次SPECT分子影像检查,并进行视觉分析和定量分析。结果:视觉分析39例CA患儿,HANS治疗前共有164处局灶性脑血流灌注和功能异常病灶,HANS治疗后131处(79.9%)完全消失或明显缩小,33处无明显变化(20.1%)。血流功能变化率(blood functional changing rate,BFCR)定量分析显示,HANS治疗CA总有效率为73.2%,同时伴有孤独症行为量表(ABC量表)总分减少和CA患儿临床症状的明显改善,认知、语言和社交能力的提高,未见明显副作用。结论:HANS治疗CA疗效显著而安全。Objectives： To evaluate the theraputic effect of HANS on childhood Autism （ CA ） with SPECT molecular imaging technology. Methods： 39 cases of CA who have adhered to HANS at least for 12 months were retrospectively analysized. Using the 100A or 200A-type HANS digital acupuncture instrument, on limbs acupoints combination, twice a day, 2 hours everyday. Examined with SPECT Molecular Imaging Technology respectively before and after treatment with HANS, and the results were analyed visually and quantitatively. Results： Visual analysis showed that 164 foci of low cerebral perfusion and function were found in 39 cases of CA children before treatment, while after treatment with HANS, 131（79.9%） completely disappeared or significantly shrinked, 33 （20.1%） no significant change. The quantitative analysis showed that the total effective rate of HANS was 73.2%, accompanied by ABC total score reduction and significant improvement in clinical symptoms, cognitive, language and social skills were also improved significantly. No significant aversive effects were observed. Conclusions： The treatment of HANS in children with CA is effective and safe.

关 键 词：儿童孤独症 针灸 HANS治疗 分子影像 

分 类 号：R749.94[医药卫生—神经病学与精神病学]