TACE联合PMCT治疗中晚期肝癌的回顾性研究  

A retrospective study on TACE combined with PMCT in treatment of advanced liver cancer

作　　者：程朋[1] 何乾文[2] 李东[1] 高辉[1] 陈滔[1] 苏晓妹[1] 李焱[1] 许涛 张涛[1] 

机构地区：[1]成都军区总医院肿瘤诊治中心,成都610083 [2]成都军区总医院放射科,成都610083

出　　处：《西南国防医药》2014年第11期1194-1196,共3页Medical Journal of National Defending Forces in Southwest China

摘　　要：目的探讨肝动脉栓塞化疗（ TACE）联合微波消融治疗（ PMCT）中晚期肝癌的临床疗效。方法选取我院2007年1月~2012年1月127例单发肿瘤直径5~8 cm的中晚期肝癌患者，分为TACE组32例和联合组（ TACE＋PMCT）95例。治疗2个周期后，通过超声造影对两组治疗效果进行评估。结果联合组中49例（51.6%）肿瘤完全灭活，46例肿瘤灭活不全；而TACE组中8例（25.4%）肿瘤完全灭活，TACE组肿瘤完全灭活率显著低于联合组（ P〈0.05）。结论 TACE联合PMCT治疗中晚期肝癌疗效优于单用TACE治疗。Objective To investigate the clinical effects of hepatic arterial chemoembolization（ TACE ）combined with percutaneous microwave coagulation therapy（ PMCT）on advanced liver cancer. Methods Total 127 medium-advanced liver cancer patients with single tumor diameter of 5-8 cm receiving treatment in our hospital from Jan. of 2007 to Jan. of 2012 were selected and divided into TACE group（n=32）and combination group（TACE＋PMCT）（n=95）. After two cycles of treatment,contrast-enhanced＆amp;nbsp;ultrasound was used to evaluate the curative effects of both groups. Results Total 49 patients in the combination group had the tumor completely inactivated（51. 6%）and 46 ones had the tumor incompletely inactivated,while eight ones in TACE group had the tumor completely inactivated（25. 4%）. The rate of complete inactivation of the patients in TACE group was significantly lower than that in the combination group（P〈0. 05）. Conclusion The curative effect of TACE combined with PMCT is better than that of only use of TACE in treatment of advanced liver cancer.

关 键 词：肝癌 微波消融 肝动脉 栓塞 化疗 疗效 

分 类 号：R735.7[医药卫生—肿瘤]