老年人轻度认知功能障碍相关影响因素调查分析  

Study on correlated influence factors inducing mild cognitive impairment of the aged patients

作　　者：祝雪利[1] 

机构地区：[1]慈溪市人民医院神经内科,浙江省315300

出　　处：《中国医院统计》2014年第5期343-345,共3页Chinese Journal of Hospital Statistics

摘　　要：目的：探讨影响老年人发生轻度认知功能障碍（ MCI）的相关因素，为早期预防提供依据。方法采用回顾性调查的研究方法，收集确诊的89例MCI患者作为病例组，同时收集89例非MCI患者作为对照组；收集各种可能影响MCI发生的危险因素，采用单因素和多因素了logistic回归法来筛选相关危险因素。结果单因素分析结果显示老年人MCI与年龄、教育程度、高血压、心脑血管疾病、糖尿病、高脂血症、高同型半胱氨酸血症（ Hhcy ）、嗜酒、性格内向、抑郁、白天过度睡眠、缺乏体育锻炼、地中海饮食等存在相关性（P＜0．05）；多因素分析结果显示年龄（OR＝2．575）、心脑血管疾病（OR＝2．793）、高同型半胱氨酸血症（OR＝2．022）、性格内向（OR＝4．679）、抑郁（OR＝2．956）、白天过度睡眠（OR＝3．340）、缺乏体育锻炼（OR＝2．643）均为MCI的危险因素。结论老年人发生MCI的危险因素包含高龄、心脑血管疾病、性格、心理、睡眠质量及体育锻炼情况。应针对可控因素进行早预防。Objective To explore correlated influence factors inducing mild cognitive impairment of the age patients, and to provide basis for early prevention.Methods With Case-control study method, we respectively collected 89 cases of MCI patients as case group, and collected 89 cases of non-MCI as control group.Different possible risk factors were collected, with single and multiple logistic regression methods screening correlated risk factors.Results Single factor analysis results showed that MCI of the aged were correlated with age, cultural level, hypertension, cardiovascular and cerebrovascular diseases, diabe-tes, hyperlipemia, hyperhomocystinemia （ HHcy） , dipsomania, introversion, depression, excessive daytime sleepiness and lack of physicial exercise （P＆lt;0.05）.Multiple factors analysis results indicated that age （OR=2.575）, cardiovascular and cerebro-vascular diseases （OR=2.793）, HHcy （OR=2.022）, introversion （OR=4.679）, depression （OR=2.956）, excessive day-time sleepiness （OR=3.340） and lack of physicial exercise （OR=2.643） were the risk factors of MCI.Conclusion The risk factors of aged MCI included high age, cardiovascular and cerebrovascular diseases, character, mental state, sleep quality and physical training, so we should take effective interventions to aim directly at these controllable risk factors.

关 键 词：老年人 轻度认知功能障碍 影响因素 危险因素 

分 类 号：R749.16[医药卫生—神经病学与精神病学]