眼眶神经鞘瘤病理组织结构与超声影像对比  

Comparison study of pathology and ultrasonics in orbital schwannomas

作　　者：朱利民 林婷婷[1,2,3] 何彦津 宋国祥[4] 

机构地区：[1]天津医科大学眼科医院 [2]天津医科大学眼视光学院 [3]天津医科大学眼科研究所,中国天津市300384 [4]天津医科大学第二医院眼科,中国天津市300384

出　　处：《国际眼科杂志》2014年第11期2028-2030,共3页International Eye Science

摘　　要：目的:本文总结44例眼眶神经鞘瘤病理分型与其B超和CDI影像学表现,分析其不同分型中囊性变和血管分布量与其在超声和CDI影像表现是否存在一定关系。方法:回顾2001-01/2008-12眼眶神经鞘瘤44例的病理和B超检查,42例CDI检查,分析各型病理含囊变例数,含血管例数及各型间比较;分析超声回声不均匀与病理所见囊变,和CDI血流情况与病理所见血管的相关性。结果:各型间比较神经鞘瘤含有囊结构为Antoni A型中较多,混合型次之,Antoni B型最少,有统计学意义(P<0.05)。含较大血管结构是Antoni B型比例最高,混合型次之,Antoni A型第三,但是缺乏统计学意义。超声显示内回声不均匀与病理见囊病的符合率为50.0%,内回声均匀,未见囊变的符合率为69.3%。CDI检查B型肿瘤查到血流信号占83.0%,A型占59.2%,两者之间无统计学意义。CDI显示较多的血流信号与病理符合率100%,有显著性差异。结论:眼眶神经鞘瘤多为A型和B型结构混合存在,以A型为主较多见,病理特征除细胞学特点外,A型区多见囊变。B型区血管多见。超声波检查内回声的改变能准确反应组织结构,其内回声的不均质性,与肿瘤内囊变区相符。CDI血流信号能准确反映肿瘤内血管分布。AIM：To summarize the pathology, B-scan ultrasound and CDI manifest of orbital neurinoma. Try to analyze the connection between the different amounts of cystic degeneration and vascular distribution and the findings in ultrasound and CDI imaging. METHODS： A retrospective analysis was performed on 44 cases with orbital neurinoma treated during January 2001 to December 2008, including 44 cases of pathological sections and B-scan ultrasound pictures, and 42 cases of CDI pictures. The connection between them were compared. RESULTS： The incidence of cystic changes in Antoni type A was the highest, mixed type followed, Antoni type B at least, which was statistical significance （P〈 0.05）. Antoni type B had more blood vessel structures, mixed type followed, Antoni type A at least, which was not statistical significance. The coincidence rate between the cystic changes and nonuniform echo in ultrosonography was 50. 0%. On the other hand, between the non-cystic changes and uniform echo, the coincidence rate was 69.3%. On CDI, 83.0% of Antoni type B and 59.2% of Antoni type A can be detected blood current with no statistical significance. CDI showed compliance rate of 100% between blood flow and pathology, with statistical significance. CONCLUSIONMixed type is the most common type in orbital neurinoma. Cystic changes are more common in Antoni type A, while blood vessel structures are more common in Antoni type B. UItrasonography can demonstrate the site, configuration and characteristics of the tumors, which is coincidence with the cystic changes and the blood vessels.

关 键 词：眼眶神经鞘瘤 病理组织 超声影像 

分 类 号：R739.72[医药卫生—肿瘤]