翼状胬肉自体角膜缘干细胞移植术后软性角膜接触镜的应用研究  

Effects of soft contact lens after pterygium surgery with limbal conjunctival autograft

作　　者：邓亚玲[1] 宋国祥[1] 梁张翼 

机构地区：[1]中国广东省深圳市第三人民医院眼科,518000

出　　处：《国际眼科杂志》2014年第11期2094-2095,共2页International Eye Science

摘　　要：目的:探讨软性角膜接触镜(SCL)应用于翼状胬肉切除自体角膜缘干细胞移植术后的有效性及安全性。方法:患者38例38眼进行了翼状胬肉切除联合自体角膜缘干细胞移植手术。随机分为两组,试验组(A组)19例19眼患者翼状胬肉切除自体角膜缘干细胞移植术后放置SCL。对照组(B组)19例19眼患者翼状胬肉切除自体角膜缘干细胞移植术后使用抗生素眼膏及绷带紧密包扎手术眼。在术后第24,48h进行观察,比较两组患者的上皮修复时间和疼痛评分。结果:在术后第24h,A组的疼痛评分:1分者12例,2分者7例,3分者0例;B组的疼痛评分:1分者6例,2分者10例,3分者3例。在术后第48h,A的疼痛评分:1分者16例,2分者3例,3分者0例;B组的疼痛评分:1分者10例,2分者7例,3分者2例。两组对比发现,A组患者在第24,48h的疼痛评分更低(P<0.05)。A组和B组的平均上皮恢复时间分别为48±0h和60.6±12h。两组在角膜修复时间上差异有统计学意义(t=4.43,P<0.01)。结论:SCL对减轻翼状胬肉切除自体角膜缘干细胞移植术后疼痛和眼睛刺痛是有效的,并且加速了角膜上皮恢复和维持了患者的日常活动。AIM： To explore the efficacy and safety of soft contact lens （ SCL ） in postoperative of pterygium surgery with limbal conjunctival autograft. METHODS： Pterygium surgery with limbal conjunctival autograft was performed to 38 eyes of 38 patients. After surgery in 19 eyes of 19 patients of group A, SCL was placed on the cornea. In 19 patients （19 eyes） of group B, antibiotic eye ointment was applied and tightly covered with bandage. Follow-up visits were performed on the 24th and 48th hour after the surgery. Re-epithelization time and pain scores were compared. RESULTS： Patients＇ 24-h pain score was 1 point for 12 cases, 2 point for 7 and 3 point for no one in group A, and 1 point for 6 ,2 point for 10 and 3 point for 3 in group B. Patients＇ 48-h pain score was 1 point for 16 cases, 2 point for 3 and 3 point for no one in group A, and 1 point for 10, 2 point for 7 and 3 point for 2 in group B. By contrast, Patients＇ pain scores for both 24-h and 48-h were lower in group A than in group B （P〈0. 05）. The mean reepithelization times in group A and B were 48±0h and 60.6± 12h, respectively. The differences in the pain score and the time of corneal reepithelization were statistically significant （ t= 4.43, P〈0.01 ）. CONCLUSION： SCL seems effective on reducing postoperative pain and eye stinging, and may accelerate, corneal re-epithelization and maintaining daily activities.

关 键 词：翼状胬肉 疼痛 软性角膜接触镜 

分 类 号：R779.6[医药卫生—眼科]