体育锻炼与乳腺癌患者生命质量的关系  

Associations between physical exercise and quality of life in breast cancer patients

作　　者：宫霄欢[1] 王继伟[1] 陈学芬[1] 石常宏[1] 孙丽[1] 张庆云[1] 袁正平 余金明[1] 

机构地区：[1]复旦大学公共卫生学院临床流行病学研究中心公共卫生安全教育部重点实验室,上海200032 [2]上海市癌症康复俱乐部,200032

出　　处：《中华肿瘤杂志》2014年第11期871-875,共5页Chinese Journal of Oncology

基　　金：上海市公共卫生重点学科建设计划资助项目（12GWZX0901）;国家社会科学基金（13CSH076）

摘　　要：目的 探讨体育锻炼与乳腺癌患者生命质量的关系,为改善乳腺癌患者的健康水平和生存状况提供参考依据.方法 2013年4月至7月在上海进行横断面研究,3 344例女性社区乳腺癌患者接受问卷调查,调查内容包括社会人口学情况、肿瘤的诊断和治疗情况、行为和生活方式等,以及欧洲癌症研究与治疗组织生命质量量表（EORTC QLQ-C30） V3.0中文版和癌症治疗功能评价量表（FACT-G）第4版中文版.结果 3 344例女性乳腺癌患者年龄为（59.25±7.94）岁,身体质量指数（BMI）为23.54±2.94,距初次诊断时间为（8.49±6.49）年.对于EORTC QLQ-C30量表,参加体育锻炼患者的躯体功能、角色功能、情绪功能及总体健康状况得分均显著高于不参加体育锻炼患者（均P＜0.05,P修正＜0.05）;参加体育锻炼患者的认知功能和社会功能得分均高于不参加体育锻炼患者,但差异无统计学意义（P ＞0.05,P修正＞0.05）;体育锻炼≥5次/周患者的角色功能、认知功能、情绪功能及总体健康状况得分均显著高于体育锻炼＜5次/周患者（均P ＜0.05,P修正＜0.05）;体育锻炼≥5次/周患者的社会功能得分高于体育锻炼＜5次/周患者,但差异无统计学意义（P ＞0.05,P修正＞0.05）;对于FACT-G量表,参加体育锻炼患者的生理状况、社会状况、情感状况、功能状况等4个维度得分以及FACT-G总分均显著高于不参加体育锻炼患者（均P＜0.05,P修正 ＜0.05）;体育锻炼≥5次/周患者的生理状况、功能状况得分以及FACT-G总分均显著高于体育锻炼＜5次/周患者（均P＜0.05,P修正＜0.05）;体育锻炼≥5次/周患者的社会状况和情感状况得分高于体育锻炼＜5次/周患者,但差异均无统计学意义（均P ＞0.05,P修正 ＞0.05）.结论 参加体育锻炼者的生命质量高于不参加体育锻炼者,提示体育锻炼对乳腺癌患者的生命质量有积极的影响,适当的体育锻炼有益于乳�Objective To investigate the associations between physical exercise and quality of life in breast cancer patients.Methods A cross-sectional study was conducted among 3 344 community breast cancer patients between April and July 2013 in Shanghai,China.Data were collected using a questionnaire,including socio-demographic situation,cancer survival and health behaviors,and scores of EORTC QLQ-C30 Simplified Chinese version and FACT-G Simplified Chinese version.Results Among a total of 3 344 breast cancer patients,the patients doing exercise reported significantly higher EORTC physical functioning scores,role functioning scores,emotional functioning scores,global health scores,and FACT-G physical well-being scores,social well-being scores,emotional well-being scores,functional well-being scores,and FACT-G total scores than the patients who didn＆#39;t take exercise（P 〈 0.05,PAdjusted 〈 0.05）.Breast cancer patients who did exercise more than or equal to 5 times/week reported significantly higher EORTC role functioning scores,cognitive functioning scores,emotional functioning scores,global health scores and FACT-G physical well-being scores,functional well-being scores,and FACT-G total scores than patients who did exercise less than 5 times/week （P 〈 0.05,PAdjusted 〈 0.05）.Conclusions There are active associations between physical exercise and quality of life in breast cancer patients.Engagement in physical exercise is beneficial to breast cancer patients with long-term survival.

关 键 词：乳腺肿瘤 生命质量 体育锻炼 

分 类 号：R737.9[医药卫生—肿瘤]