脉络膜厚度在青光眼发生发展中的作用研究进展  

Recent advances in the effect of choroidal thickness in the development and progression of glaucoma

作　　者：张正威[1] 张亦农[1] 

机构地区：[1]江苏省无锡市第二人民医院眼科 南京医科大学附属无锡第二医院眼科,214002

出　　处：《中华眼视光学与视觉科学杂志》2014年第10期636-640,共5页Chinese Journal Of Optometry Ophthalmology And Visual Science

基　　金：无锡市卫生局科研项目计划（Q201309）

摘　　要：由于青光眼性视神经病变与供应视神经的血流异常有关,而视乳头筛板前区的血液供应主要来自视乳头周边的脉络膜血管分支,因此,青光眼和脉络膜血流之间的关系一直都备受关注.此外,在青光眼发病机制方面,脉络膜膨胀增厚也被认为是诱发急性闭角型青光眼的原因之一.随着频域OCT（SD-OCT）深度增强成像（EDI）技术应用,临床上已能在活体状态下较为准确地测量人体眼球的脉络膜厚度.笔者对SD-OCT深度增强成像技术所获得的青光眼患者脉络膜厚度方面的研究做一综述,并进一步探讨脉络膜在青光眼发生、发展中的作用.It is generally accepted that abnormal blood supply to the optic nerve is involved in glaucomatous optic neuropathy.Since the blood supply of the prelaminar area of the optic nerve head originates from branches within the peripapillary choroid,the relationship between glaucoma and choroidal blood flow has attracted much attention.Moreover,in terms of the pathogenesis of glaucoma,choroidal expansion is regarded as one of the contributing factors that induce an acute attack of primary angle-closure glaucoma.With the use of enhanced depth imaging spectral-domain optical coherence tomography,the human choroid can be measured accurately in vivo in the clinic.In this article,we review the study of choroidal thickness in glaucoma patients,and further discuss the role of the choroid in the development and progression of glaucoma.

关 键 词：体层摄影术 光学相干 深度增强成像 脉络膜厚度 青光眼 

分 类 号：R775[医药卫生—眼科]