肝脏DCE-MR技术及其在肝恶性肿瘤血管靶向治疗中的应用  

Dynamic contrast-enhanced magnetic resonance imaging of the liver: Applications in treatment of hepatic malignancies with vascular targeting agents

作　　者：陈娟[1] 尹化斌[1] 

机构地区：[1]复旦大学附属上海市第五人民医院放射科,上海市200240

出　　处：《世界华人消化杂志》2014年第32期4928-4933,共6页World Chinese Journal of Digestology

摘　　要：肝脏动态增强磁共振(dynamic contrastenhanced magnetic resonance,DCE-MR)成像技术是一种新兴的技术,可评价肝组织及肿瘤的灌注及血管特征,用于多种弥漫性及局灶性肝脏病变,在肝恶性肿瘤血管靶向治疗中的应用价值尤其明显.本文将介绍肝脏DCE-MR半定量分析技术、常见定量分析的模型、常用对比剂并重点综述其在血管靶向治疗中的临床应用.Dynamic contrast-enhanced magnetic resonance （DCE-MR） imaging of the liver as a trendy tech- nique can be applied in various kinds of liver dis- eases to evaluate perfiasion and vascular character- istics of liver tissue and tumor. It has been proved that DCE-MR imaging plays an important role in the treatment of liver malignancies with vascular targeting agents. This review aims to give an over- view of DCE-MR imaging of the liver in terms of semi-quantitative analysis methods, common quan- titative analysis models and contrast agents and discuss its application value in the treatment of liver malignancies with vascular targeting agents.

关 键 词：磁共振成像 对比剂 肝肿瘤 药物治疗 

分 类 号：R735.7[医药卫生—肿瘤] R445.2[医药卫生—临床医学]