行为疗法加氟桂利嗪预防性治疗儿童偏头痛效果观察  

Preventive effect of behavioral therapy plus flunarizine in children with migraine

作　　者：陈言钊[1,2] 李宁 周克英 

机构地区：[1]暨南大学第二临床医学院 [2]深圳市人民医院儿科,广东深圳518020 [3]南方医科大学附属深圳市妇幼保健院儿科,广东深圳518000

出　　处：《中国当代儿科杂志》2014年第11期1105-1108,共4页Chinese Journal of Contemporary Pediatrics

摘　　要：目的探讨行为疗法加氟桂利嗪预防性治疗儿童偏头痛的临床效果。方法 2011年1月至2014年1月就诊的90名偏头痛患儿随机分为治疗组(45例)和对照组(45例),对照组接受口服氟桂利嗪治疗,治疗组采用行为疗法同时口服氟桂利嗪,应用儿童偏头痛残疾程度评分(PedMIDAS)及改良Bussone头痛指数连续3个月观察治疗效果。结果治疗前两组间PedMIDAS值差异无统计学意义(P>0.05),治疗后3个月治疗组PedMIDAS值显著低于对照组(16±8 vs 20±10,P<0.05)。治疗前两组间改良Bussone头痛指数值差异无统计学意义(P>0.05),治疗后3个月治疗组改良Bussone头痛指数值显著低于对照组(25±18 vs 37±21,P<0.05)。结论行为疗法加氟桂利嗪预防性治疗儿童偏头痛较单用氟桂利嗪有更好的效果,可考虑临床推广应用。Objective To investigate the preventive effect of behavioral therapy plus lfunarizine in children with migraine. Methods Ninety pediatric patients with migraine between January 2011and January 2014 were randomly divided into treatment group （45 cases） and control group （45 cases）. The treatment group received behavioral therapy in addition to oral lfunarizine, while the control group received oral lfunarizine alone. All patients were followed up for 3 months to evaluate the therapeutic effect by the Pediatric Migraine Disability Assessment Score （PedMIDAS） and improved Bussone headache index. Results There were no signiifcant differences in PedMIDAS （P〉0.05） and improved Bussone headache index （P〉0.05） between the control and treatment groups before treatment. Significant differences were observed in PedMIDAS （16±8 vs 20±10;P〈0.05） and improved Bussone headache index （25±18 vs 37±21;P〈0.05） between the two groups after 3 months of treatment. Conclusions Preventive treatment of behavioral therapy plus oral lfunarizine shows a better clinical efifcacy than oral lfunarizine alone in children with migraine and holds promise for clinical application.

关 键 词：偏头痛 预防性治疗 行为疗法 儿童 

分 类 号：R747.2[医药卫生—神经病学与精神病学]