角膜塑形术后地形图的傅立叶分析  

Fourier analysis of corneal topography after overnight orthokeratology

作　　者：梁莉[1] 温跃春[1] 顾永昊[1] 周末[1] 鲍建[1] 董琼[1] 

机构地区：[1]安徽医科大学附属省立医院眼科,合肥230001

出　　处：《安徽医科大学学报》2014年第12期1759-1761,共3页Acta Universitatis Medicinalis Anhui

基　　金：安徽省自然科学基金(编号:1208085QH167)

摘　　要：目的运用傅立叶分析地形图观察角膜塑形术对角膜表面光学特性的影响,探索这一定量分析方法是否可以作为术前术后动态评估的有效模式。方法选取38例患者(75眼),平均等效屈光度范围为-0.75^-6.00 D。采用夜戴型角膜塑形镜矫治近视,分别在配戴角膜塑形镜前、戴镜后1个月进行角膜地形图检查,通过Fourier Map模式对Fourier index(傅立叶指数)的0次球面部分(Spherical)、1次非对称性部分(Asymmetry)、2次规则散光部分(Reg.Astig)和3次以上高次非规则散光部分(Higher order)等4种组成部分数据进行对比分析。结果戴镜1个月后,角膜中央3、6 mm范围Spherical的平均值与基线水平相比,差异有统计学意义(t=19.19、18.745,P<0.01)角膜中央3、6 mm范围Reg.Astig的平均值与基线水平相比,差异无统计学意义(t=1.909、0.773,P>0.05);角膜中央3、6 mm范围Asymmetry的平均值与基线水平相比,差异有统计学意义(t=-6.289、-9.436,P<0.01);角膜中央3、6 mm范围Higher order的平均值与基线水平相比,差异有统计学意义(t=-3.248、-4.909,P<0.01)。结论傅立叶分析模式反映了角膜塑形术后角膜中央3、6 mm区域光学特性的变化,是角膜塑形术有效的定量分析模式。Objective To investigate optical property changes in corneal surface of orthokeratology lens wearers by using fourier analysis and to explore whether this method can be used to evaluate effectiveness of the treatment.Methods 38 myopic patients （total of 75 myopic eyes） wore reverse-geometry OK lenses every night for 1 month.Corneal morphology was measured by TMS-4.Baseline and 1 month follow-up data were collected and analyzed.The Fourier indices including Spherical,Asymmetry,Reg.Astig and higher order irregularity were obtained by Fourier Map.Results After wearing OK lenses for one month,the mean of spherical average of the central 3 mm and 6 mm corneal declined and both were statistically significant（t =19.19,18.745; P ＜0.01）.The average of Reg.Astig of central 3 mm and 6 mm corneal declined and both were not statistically significant（t =1.909,0.773 ; P ＞ 0.05）.The average of Asymmetry of the central 3 mm and 6 mm corneal increased and both were statistically significant（t =-6.289,-9.436;P ＜0.01）.The average of higher order of the central 3 mm and 6 mm corneal increased and both were statistically significant （t =-3.248,-4.909,P ＜ 0.01）.Conclusion Fourier analysis is an effective method to calculate corneal optical changes of both 3 mm and 6 mm corneal surface areas after orthokeratology treatment.

关 键 词：角膜塑形术 角膜地形图 傅立叶分析 

分 类 号：R778.3[医药卫生—眼科] R770.4[医药卫生—临床医学]