1138例胃癌临床病理特征分析  

Analysis of clinicopathologic characteristics in 1138 cases of gastric adenocarcinoma

作　　者：司岑[1] 杨艳丽[2] 李华[2] 马晓娟[2] 胡建国[1] 

机构地区：[1]宁夏医科大学总医院消化内科,宁夏银川750004 [2]宁夏医科大学,宁夏银川750004

出　　处：《宁夏医学杂志》2014年第11期982-984,共3页Ningxia Medical Journal

基　　金：宁夏自然科学基金资助项目(NZ08101);宁夏留学人员科技活动项目(2009317)

摘　　要：目的总结胃腺癌患者的临床病理资料特点。方法回顾性统计1 138例胃腺癌患者的一般资料、癌灶发生部位、肿瘤分化程度等特点,分析各分类变量之间的相关性。结果 1 138例胃腺癌患者平均年龄（59.91±11.51）岁,中位年龄60岁（22~86岁）,肿瘤高发年龄50~70岁（60.89%）,男女性别之比为3.31∶1,汉回民族比为4.87∶1。所有患者中贲门胃底癌381例（33.48%）,胃体癌351例（30.84%）,胃窦角癌406例（35.68%）;组织学分型中有低分化腺癌634例（55.71%）,中分化284例（24.96%）,高分化220例（19.33%）;其中检出早期胃癌78例（6.85%）,进展期癌1060例（93.15%）;胃腺癌患者的年龄与性别、癌灶发生部位、肿瘤分化程度有关（P〈0.05）,民族与肿瘤分化程度有关（P〈0.05）;性别与癌灶发生部位有关（P〈0.05）。结论年轻患者较老年患者,回族患者较汉族患者低分化腺癌比重大、恶性程度高。Objective To provide reliable foundations on the diagnosis and treatment of gastric adenocarcinoma through the summarizing and analyzing the clinicopathologic characteristics of it from the General Hospital of Ningxia Medical University. Methods By selecting 1138 patients with gastric adenocarcinoma （ treated by our department from Mar. 2009 to Sep. 2011 ）, the clinic pathologic characteristics of all the samples, such as basic data, tumor location and degree of differentiation were analyzed retrospectively. The rela- tivity among the categorical variables was also analyzed by use of chi - square analysis method. Results The age of all the 1138 patients ranged from 22 to 86 with the average age of 59.91 ＋ 11.51 and medium age of 60. The peak onset age of the disease ranged from 50 to 70 with the percentage of 60.89%. Among all the patients selected,the ratio of the male （874） and female （264） was 3.31：1 ,and the nationality of 944 samples was Han and 194 samples was Hui, and its ratio was 4.87：1. Among the 1138 carcinoma patients, there were 381 （33.48%） patients suffered from cardia gastric cancer,351 （30.84%） patients suffered from gastric cancer and 406 （35.68%） patients suffered from antrum cancer. As for degree of the pathological differentiation,220 （ 19.33% ） cases were high differentiate ade- nocarcinoma, and 282 （24.96%） cases were moderate differentiation and 634 （55.71%） cases were low differentiate adenocarcinoma among the 1138 cases. Refer to the staging of tumor,78 （6.85%） patients were diagnosed as early gastric cancer and 1060 （93.15%） patients are advanced gastric cancer. The statistical analysis showed that sex composition, tumor location and the degree of the pathologi- cal differentiation were related to the age of the patients （ P 〈 0. 05 ） ： the analysis denoted that the degree of the pathological differentia- tion had the relativity to nationality of the patients （ P 〈 0.05 ）, and the tumor location had correlation with sex com

关 键 词：胃腺癌 临床病理特征 趋势 

分 类 号：R735.2[医药卫生—肿瘤]