甲状腺再手术中应用纳米碳保护甲状旁腺的分析  

作　　者：徐锦[1] 郭幕红 姜鹏[1] 张斌[1] 

机构地区：[1]江苏省南京市第一医院,210000

出　　处：《浙江临床医学》2014年第11期1742-1743,共2页Zhejiang Clinical Medical Journal

摘　　要：目的：探讨在甲状腺再手术中应用纳米碳混悬液，对甲状旁腺保护的作用。方法21例甲状腺再手术患者，随机分为观察组（纳米碳组）11例和对照组10例，观察组在术中先向残余甲状腺或癌灶周围注射纳米碳，对照组不使用纳米碳，观察两组辨别甲状旁腺的差异。结果观察组使甲状腺再手术患者的残余甲状腺或癌灶黑染，而甲状旁腺不黑染，在黑染组织中均未发现甲状旁腺，术后甲状旁腺减退的并发症实验组较对照组显著降低（P〈0.05）。结论纳米碳对甲状腺再手术中的甲状旁腺的负显影，使甲状旁腺易于识别和保护，明显降低一过性甲状旁腺功能减退的并发症。Objective To explore the role and value of carbon nanoparticles suspension in thyroid reoperation for protecting parathyroid gland. Methods Totally 21 patients undergoing thyroid reoperation in department of breast and thyroid surgery of The first hospital of Nanjing City from Jan.2012 to Feb.2014 were chosen and randomly divided into experimental group（carbon nanoparticles group,n=11）and control group（n=10）.The experimental group was injected with 0.3-0.5ml carbon nanoparticles in residual thyroid or tumor lesion during surgery,while the control group was not given carbon nanoparticles.The difference of identifying parathyroid gland of two groups was observed. Result Residual thyroid or tumor lesion during surgery and Lymphnodes of VI group were stained black by carbon nanoparticles and parathyroid gland was not stained black.No parathyroid gland was found in the black-stained tissue.And the incidence of postoperative complications such as transient hypoparathyroidism in experiment group decreased significantly（P〈0.05）.Conclusion In thyroid carcinoma reoperation,carbon nanoparticles for negative development of parathyroid gland can make parathyroid gland easy to be identif ied and protect, and reduce the incidence of complications such as transient hypoparathyroidism.

关 键 词：纳米碳 甲状腺手术 甲状旁腺 

分 类 号：R736.105[医药卫生—肿瘤]