基于气质联用技术的唾液乳杆菌渗胁迫响应代谢组学研究  

GC/MS Based Metabonomics Study on Osmotic Response of Lactobacillus salivarius

作　　者：龚霄[1,2] 齐宁利[1] 林丽静[1] 陈晶瑜[2] 韩北忠[2] 

机构地区：[1]中国热带农业科学院农产品加工研究所,广东湛江524001 [2]中国农业大学食品科学与营养工程学院,北京100083

出　　处：《食品研究与开发》2014年第19期10-12,共3页Food Research and Development

基　　金：中国热带农业科学院院本级基本科研业务费专项资金(1630062014019);十一五国家科技支撑计划课题支持(2006BAD04A06)

摘　　要：采用气质联用技术分析了高渗胁迫下唾液乳杆菌胞内代谢物变化,结果表明:不同细胞代谢模式下,氨基酸类、有机酸类、脂肪酸类、胺类和糖类及其衍生物等具有显著差异,这些代谢物直接参与了细胞渗透胁迫响应相关的主要生化反应和关键代谢通路。In this work, intracellular metabolite profiles of Lactobacillus salivarius on hypertonic stress were analyzed using GC/MS method, and the result showed amino acids, organic acids, fatty acids, amines, and sugars and their derivatives were significantly different between different metabolic models , which were directly involved in the cell response to osmotic stress-related biochemical reactions and key metabolic pathways.

关 键 词：唾液乳杆菌 渗透胁迫响应 气质联用 代谢组学 

分 类 号：O657.63[理学—分析化学] TS201.3[理学—化学]