远端胆管癌的治疗进展  

Treatment of distal cholangiocarcinoma

作　　者：徐艺[1] 王浩[1] 崔云甫[1] 

机构地区：[1]哈尔滨医科大学附属第二医院普外科,黑龙江省哈尔滨市150086

出　　处：《世界华人消化杂志》2014年第28期4263-4269,共7页World Chinese Journal of Digestology

基　　金：黑龙江省科技厅攻关基金资助项目;No.GC12C304-1;黑龙江省留学回国人员科技项目择优基金资助项目;No.2011297~~

摘　　要：远端胆管癌是一少见但侵袭性强的恶性肿瘤,其发病率逐年上升.病理类型大多为腺癌,倾向于侵袭邻近脏器及发生局部淋巴结转移.目前,手术切除仍是唯一可能治愈的方法.但是,由于血管受侵或发生远处转移,手术切除率仅为21%-96%且预后不理想.因此,针对远端胆管癌的各种治疗手段成为近年研究的热点.本文就远端胆管癌的根治性手术、姑息性手术、介入治疗、辅助治疗的进展作一综述.Distal cholangiocarcinoma（DCC） is a rare,aggressive malignancy with an increasing in-cidence during past few years. The great ma-jority of distal bile duct cancers are adenocar-cinomas that preferentially invade adjacent or-gans and metastasize to regional lymph nodes.Surgical resection remains the only potentiallycurative treatment at present. Nevertheless,resectability rates range from 21% to 96% ei-ther due to local vascular invasion or distantmetastasis. Therefore, DCC is related with apoor prognosis. Thus, new treatments for DCCare becoming a hot spot of research in recentyears. This article reviews the progress in thetreatment of DCC in terms of radical surgery,palliative surgery and interventional therapyas well as adjuvant therapy.

关 键 词：胆管 远端胆管癌 治疗 肿瘤 

分 类 号：R735.8[医药卫生—肿瘤]