红外自发荧光与相干光断层扫描在后极部脉络膜裂伤应用  

The application of near-infrared autofluorescence and optical coherence tomography in the posterior pole of the retina with choroidal rupture

作　　者：李士清[1] 牛超[1] 王志立[1] 雷祥[1] 郭慧丽[1] 李晓华[1] 

机构地区：[1]河南省眼科研究所&河南省立眼科医院,郑州450003

出　　处：《中国实用眼科杂志》2014年第11期1338-1341,共4页Chinese Journal of Practical Ophthalmology

基　　金：国家自然科学基金（81100650）

摘　　要：目的 探讨近红外自发荧光（NIA）联合相干光断层扫描（OCT）检查在视网膜后极部脉络膜裂伤中的应用价值.方法 对2009年2月至2014年4月在河南省立眼科医院确诊为视网膜后极部脉络膜裂伤11例患者进行眼底荧光血管造影（FFA）、NIA和OCT检查,并统计FFA和NIA测量脉络膜裂伤程度结果.结果 8例视网膜后极部脉络膜裂伤未合并视网膜下出血患者FFA与NIA均能从平面显示脉络膜裂伤长度,两组数据比较差异无统计学意义（t =1.06,P=0.31＞0.05）.OCT从切面显示脉络膜裂伤及与黄斑中心凹距离.3例视网膜后极部脉络膜裂伤合并视网膜下出血患者NIA和OCT能立体评估和随访视网膜下出血位置及隆起高度的变化.NIA联合OCT检查所需时间约为FFA的35.56％,所需费用为FFA的38.64％.结论 NIA和OCT为无创性检查,两者联合能更简单和经济评估后极部脉络膜裂伤及合并视网膜下出血的患者.Objective To explore the clinical significance of near-infrared autofluorescence （NIA） combined with optical coherence tomography （OCT） in patients with choroidal rupture in the posterior pole of the retina.Methods Eleven （11 eyes） with choroidal rupture or combined with subretinal hemorrhage in the posterior pole of the retina were examined by fundus fluorescein angiography （FFA）,NIA and OCT inspection,and recorded the results of the length of the choroidal rupture measured respectively on NIA and FFA images.Results Both FFA and NIA could show the choroidal ruptures in 8 patients with no subretinal hemorrhage,there were no significant differences between the two groups in the length measure of the choroidal rupture （t =1.06,P =0.31＞0.05）.OCT could display the location of the choroidal rupture and the relationship with macular fovea from section.NIA combined with OCT could bring a three-dimensional evaluation and follow-up the change of subreitnal hemorrhage in 3 patients with choroidal rupture.The examination time of NIA combined with OCT was about 35.56％ of FFA,and the cost was about 38.64％ of FFA.Conclusions NIA and OCT are both noninvasive examination,NIA combined with OCT can bring a more simple and economic assessment patients with choroidal rupture or combined with subretinal hemorrhage in the posterior pole of the retina.

关 键 词：近红外自发荧光 相关光断层扫描 眼底血管造影 脉络膜裂伤 

分 类 号：R779.63[医药卫生—眼科]