骨钙素与低强度激光对正畸牙移动速度的影响研究  

Application of osteocalcin and low-energy laser in the acceleration of experimental rat tooth movement

作　　者：华小川[1] 杨苹[1] 周治[1] 刘晓君[1] 

机构地区：[1]云南省第二人民医院口腔正畸科,昆明650021

出　　处：《国际口腔医学杂志》2015年第1期16-18,共3页International Journal of Stomatology

基　　金：云南省应用基础研究面上项目(2010ZC222)

摘　　要：目的探讨骨钙素和低强度激光照射作用对正畸牙移动的影响。方法取96只SD大鼠,分为A、B、C、D四个组,每组24只。A组:放置矫治装置后,每天在大鼠加力磨牙腭侧注入1 mg大鼠纯化骨钙素。B组:在放置矫治装置后,每天用弱激光照射被移动的磨牙。C组:在放置矫治装置的当天,每天在大鼠加力磨牙腭侧注入1 mg骨钙素,同时用弱激光照射。D组(对照组):只放置矫治装置给大鼠磨牙加力,不采取其他措施。分别测量各组大鼠加力后1、3、5、7、10、14 d牙齿的移动距离,并进行苏木精-伊红染色观察。结果 C组大鼠牙移动的距离明显大于其他3个组(P<0.05);与D组比较,C组压力侧破骨现象明显,张力侧成骨活跃。结论骨钙素与激光共同作用有效地加速了实验性大鼠的正畸牙移动。Objective To study the effects of both osteocalcin（OC） and low-energy laser in the movement of experimental rat tooth. Methods A total of 96 SD rats were separated into four groups. In group A, the rats were injected daily withl μg of OC into the palatal bifurcation site of the first molar. In group B, the rats were irradiated daily by low- energy laser during tooth movement. In group C, the rats were injected with OC and were irradiated by low-energy laser daily.. Group D was the control group. The distance of the first molar movement was measured on the model. All values were statistically analyzed. Results The tooth movement in group C was greater than that in the other groups（P〈0.05）. Compared with group D, group Chad more broken bones up on lateral pressure and had more active osteogenesis on the tension side. Conclusion Periodontal diseases correlate with gestational diabetes mellitus, and periodontitis may be a risk factor of gestational diabetes mellitus.

关 键 词：骨钙素 激光 正畸学 牙移动 

分 类 号：R783.5[医药卫生—口腔医学]