坏死性胰腺炎的微创治疗进展  

Progress of treatment on necrotizing pancreatitis by minimally invasive

作　　者：崔光星 刘冰熔[1] 

机构地区：[1]哈尔滨医科大学附属第二医院消化内科,黑龙江哈尔滨150086

出　　处：《胃肠病学和肝病学杂志》2014年第11期1365-1368,共4页Chinese Journal of Gastroenterology and Hepatology

摘　　要：急性胰腺炎(acute pancreatitis,AP)是临床常见的急腹症,由各种病因导致胰酶的激活,以胰腺的局部炎症反应为特征,伴或不伴有其他器官功能改变的疾病。其中,约20%的AP可发展为坏死性胰腺炎(necrotizing pancreatitis,NP),病死率高,预后差。近年来,随着科学研究的深入,治疗NP的手术方式,也得到了快速的发展。其手术方式由传统的开腹手术,逐步发展为微创介入治疗,包括CT引导下经皮导管引流术、经胃内镜下清创引流术、微创外科清创术等,有效降低了NP患者的病死率,提高了患者的生存质量。本文就NP的最新微创治疗进展做一综述。Acute pancreatitis （AP） is a common acute abdominal disease in clinic,which is characterized by inflammatory response of local pancreas,and caused by activation of pancreatic enzymes by multiple factors,accompanied with or not other organ functional changes.About 20％ of AP in total can develop into necrotizing pancreatitis （NP） which is high in mortality and has a poor prognosis.In recent years,with the advances of the scientific research,the surgical treatments of AP has also made a great progress,which is changing into minimally invasive approaches from primary open surgery,including CT-guided percutaneous drainage catheter,endoscopic transgastric drainage or necrosectomy,minimally invasive surgical necrosectomy.The minimally invasive approaches effectively reduce the mortality and improve patients＇ prognosis.In this article,we review the recent minimally invasive advances of NP treatments.

关 键 词：急性胰腺炎 坏死性胰腺炎 经皮导管引流 经胃内镜下坏死组织清除术 微创腹膜后坏死组织清除术 

分 类 号：R576[医药卫生—消化系统]