祛痰活血疏肝法治疗非酒精性脂肪性肝炎疗效总结  

Phlegm-eliminating and Blood-promoting and Liver-soothing Method in treatment of Nonalcoholic Steatohepatitis

作　　者：刘菊容[1] 朱晓宁[1] 汪静[1] 米绍平[1] 张光海[1] 

机构地区：[1]泸州医学院附属中医医院肝胆病科,四川泸州646000

出　　处：《辽宁中医药大学学报》2014年第12期128-130,共3页Journal of Liaoning University of Traditional Chinese Medicine

基　　金："十一五"国家中医药管理局"名老中医传承工作室建设项目"(国中医药人教发[2010]59号);四川省泸州市科技局重点科技项目[2010-s-15(1/8)];四川省教育厅重点项目(10ZA154)

摘　　要：目的：总结祛痰活血疏肝法治疗非酒精性脂肪性肝炎（NASH）的疗效,为中医药治疗NASH提供有效的方法。方法：52例患者采用祛痰活血疏肝法治疗,疗程4~12周。比较治疗前后谷丙氨酸转移酶（ALT）、门冬氨酸转移酶（AST）、谷氨酰转肽酶（r-GT）、甘油三酯（TG）、胆固醇（Tch）、低密度脂蛋白（LDL-c）等理化指标及肝脏彩超等变化。结果：治疗后痊愈18例,显效16例,有效12例,无效6例,总有效率88.00%,未见明显的不良反应,P〈0.01。治疗后患者谷丙氨酸转移酶、门冬氨酸转移酶、谷氨酰转肽酶、甘油三酯、胆固醇、低密度脂蛋白各项指标下降明显,具有统计学意义（P〈0.01）。结论：祛痰活血疏肝法治疗非酒精性脂肪性肝炎安全有效。Objective ： To investigate the curative effect of phlegm-ellminating and blood-promoting and liver-soothing method in the treatment of nonalcoholic steatohepatitis （ NASH ）. Methods ： 52 cases were treated by phlegm-eliminating and blood-promoting and liver-soothing method for 3 months. We observed the alanine amino transferase, nmda translerase, GGTP （gamma, glutamyl, transpeptidase ）, triglyceride, cholesterol, lowdensity lipoprotein cholesterol （ hdl-c ）, liver exceeds indicators comparison before and after treatment. Results： 18 patients were recoveried after treatment. 16 cases had marked effect. 12 cases were effectively,6 with no effeet and the total effective rate 88.00% with no obvious adverse reactions （ P〈0.01 ）. After treatment, alanine amino transferase, nmda transferase, GGTP （ gamma glutamyl transpeptidase ）, triglyceride, cholesterol and low density lipoprotein decreased significantly. Conclusion：The phlegm- eliminating and blood-promoting and liver-soothing method is safe and effective in treatment of nonalcoholic steatohepatitis.

关 键 词：非酒精性脂肪性肝炎 祛痰活血疏肝法 祛痰活血汤 中药疗效 

分 类 号：R575.1[医药卫生—消化系统]