直肠系膜来源恶性黑色素瘤1例并文献复习  

Malignant Melanoma of Mesorectum Origin：One Case Report and Literature Review

作　　者：王涛[1] 杨熊飞[1] 杜斌斌[1] 张维胜[1] 冯丽莉[1] 向振东[1] 

机构地区：[1]甘肃省人民医院肛肠科,甘肃兰州730000

出　　处：《中国肛肠病杂志》2014年第11期18-21,共4页Chinese Journal of Coloproctology

摘　　要：为探讨直肠系膜来源恶性黑色素瘤的临床诊治及预后，报道1例直肠系膜来源恶性黑色素瘤，对其进行光镜观察、免疫组织化学染色，并复习相关文献，探讨该病的临床特点。结果显示，患者行全直肠系膜切除术（TME）加直肠前切除吻合术（Dixon）。解剖标本，肿瘤来自直肠系膜，向肠腔内浸润生长，并穿透肠壁全层，系膜内包裹大量墨汁样液体，有臭味。病理证实恶性黑色素瘤。术后随访4个月复查有局部复发及远处转移。患者术后8个月死亡。结果表明，直肠系膜来源恶性黑色素瘤临床极为罕见，确诊依靠病理检查及免疫组化，治疗手段以手术切除为主，但总体预后不佳。This study was to discuss the clinical diagnosis,treatment and prognosis of malignant melanoma of mesorectum origin, one case was presented in this paper. I.ight microscopy and immunohistochemistry staining were performed,and the relevant literature was reviewed to discuss the clinical features of this disease.As results, the patient underwent total mesorectal excision（TME） and Dixon surgery, whose anatomical specimens showed that neoplasm was from mesorectum, growing invasively into the intestinal cavity and penetrating the full thickness of the intestinal wall,with a large amount of ink -like liquid with smelly wrapped in the mesentery.It was confirmed pathologically as malignant melanoma.After a 4 month followup,local recurrence and remote metastasis occurred. The patient died 8 months later, h is concluded that malignant melanoma of mesorectum origin is extremely rare in clinical practice,and its diagnosis relies on pathology and immunochemistry, surgical excision is the major treatment, but the overall prognosis is poor.

关 键 词：直肠系膜 恶性黑色素瘤 全直肠系膜切除术 

分 类 号：R735.37[医药卫生—肿瘤]