刷牙诱导癫:二例报告并文献复习  

Toothbrushing-induced epilepsy:two cases report and review of literature

作　　者：周春雷[1] 罗晶[2] 李晓民[1] 王艳[1] 赵德明[1] 

机构地区：[1]安徽省淮北市人民医院神经内科,235000 [2]重庆医科大学附属第一医院神经内科,400016

出　　处：《中国现代神经疾病杂志》2014年第12期1087-1090,共4页Chinese Journal of Contemporary Neurology and Neurosurgery

摘　　要：目的探讨刷牙诱导癫的诱发因素、临床表现、治疗及预后。方法与结果 2例患者系同胞姊妹,均为刷牙诱导癫发作,表现为口面部抽搐、单侧上肢抽搐伴意识丧失,数分钟后恢复,1例伴舌咬伤,神经系统检查正常。头部MRI无异常,脑电图1例正常、1例呈现发作间期尖-慢复合波。均未行抗癫药物治疗,嘱其避免用力刷牙、缩短刷牙时间后完全控制发作。结论刷牙诱导癫是一种少见的反射性癫,癫发作与刷牙呈锁时关系,轻症患者降低刺激强度即可完全控制发作。Objective To discuss the major indicing factors, clinical features, therapy and prognosis of toothbrushing - induced epilepsy. Methods The clinical manifestations, auxiliary examinations, treatment and prognosis were studied in 2 patients of toothhrushing-induced epilepsy, and related literatures were reviewed. Results Two sisters with toothbrushing-induced epilepsy were recruited in our study. Seizures began with facial numbness and convulsive tic, then involving right arm tic, and followed by loss of consciousness. One case was associated with tongue bite. They recovered after a few minutes without administration of any antiepileptic drugs （AEDs）. Physical and neurological examination and brain MRI scan were normal. Prolonged video EEG （VEEG） recordings during wakefulness and sleep showed normal in the older sister, and spike-slow waves in the younger sister. After brushing their teeth less vigorously in shorter time, no seizure occurred. The patients had no further seizures during follow-up. Conclusions Toothbrushing-induced epilepsy is a rare kind of reflex epilepsy, and has tightly time-locked relationship with toothbrushing. Mild cases can be released by avoiding prolonged and vigorous brushing.

关 键 词：癫痫 反射性 刷牙 

分 类 号：R742.1[医药卫生—神经病学与精神病学]