神经内分泌肿瘤肝转移的外科治疗进展  

Advances in Surgical Management of Neuroendocrine Liver Metastasis

作　　者：胡军[1] 沈先锋[1] 谭巧玲[1] 菅志远[1] 

机构地区：[1]湖北医药学院附属太和医院普外一科,湖北十堰442000

出　　处：《中国普外基础与临床杂志》2014年第12期1593-1597,共5页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的探讨神经内分泌肿瘤肝转移的外科治疗进展。方法搜集国外有关神经内分泌肿瘤肝转移外科治疗的文献并作综述。结果神经内分泌肿瘤肝转移的外科治疗的效果已得到证实,但由于肿瘤形成的分子机理较为复杂,术后复发率较高,新的治疗方法被大量开发并应用于临床,目前已取得了不错的疗效。这些治疗方法包括:外放射治疗、内放射治疗、肝移植及分子靶向治疗。结论对神经内分泌肿瘤肝转移进行综合性治疗,将成为今后外科治疗神经内分泌肿瘤肝转移的方向。Objective To evaluate the effect of surgical management of neuroendocrine liver metastasis. Methods Literatures about the surgical management of neuroendocrine liver metastasis were collected and reviewed. Results Effect of surgical treatment for neuroendocrine liver metastasis was confirmed, but the molecular mechanism of tumor formation was more complex, and the recurrence rate of surgery was too high, so a large number of new treatment methods had been developed and used clinically, and had achieved good results. These treatments included external beam radiotherapy, internal radiotherapy, liver transplantation, and targeted therapies. Conclusion Comprehensive surgical management will be the direction of surgical management of neuroendocrine liver metastasis.

关 键 词：神经内分泌肿瘤 肝转移 治疗 

分 类 号：R735.7[医药卫生—肿瘤]